Despite the growing constellation of genetic loci linked to common traits, these loci have yet to account for most heritable variation, and most act through poorly understood mechanisms. Recent machine learning (ML) systems have used hierarchical bio...
While the construction of a dependable force field for performing classical molecular dynamics (MD) simulation is crucial for elucidating the structure and function of biomolecular systems, the attempts to do this for glycans are relatively sparse co...
The measurement and quantification of glucose concentrations is a field of major interest, whether motivated by potential clinical applications or as a prime example of biosensing in basic research. In recent years, optical sensing methods have emerg...
OBJECTIVE: The prevention of hypertension in primary care requires an effective and suitable hypertension risk assessment model. The aim of this study was to develop and compare the performances of three machine learning algorithms in predicting the ...
Computational and mathematical methods in medicine
36118835
We aimed to identify the glucose metabolism statuses of nondiabetic Japanese adults using a machine learning model with a questionnaire. In this cross-sectional study, Japanese adults (aged 20-64 years) from Tokyo and surrounding areas were recruited...
Mathematical biosciences and engineering : MBE
36031985
Glucose management for people with type 2 diabetes mellitus is essential but challenging due to the multi-factored and chronic disease nature of diabetes. To control glucose levels in a safe range and lessen abnormal glucose variability efficiently a...
BACKGROUND: Age is the strongest risk factor for dementia and there is considerable interest in identifying scalable, blood-based biomarkers in predicting dementia. We examined the role of midlife serum metabolites using a machine learning approach a...
Nonenzymatic biosensors hold great potential in the field of analysis and detection due to long-term stability, high sensitivity, and low cost. However, the relative low selectivity, especially the overlapped oxidation peaks of biomarkers, in the bio...
Analytical methods : advancing methods and applications
36373210
Colorimetric paper sensors are used in various fields due to their convenience and intuitive manner. However, these sensors present low accuracy in practical use because it is difficult to distinguish color changes for a minute amount of analyte with...
The stability of biopharmaceutical therapeutics over the storage period/shelf life has been a challenging concern for manufacturers. A noble strategy for mapping best and suitable storage conditions for recombinant human serum albumin (rHSA) in labor...