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Head and Neck Neoplasms

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Deep learning algorithm performance in contouring head and neck organs at risk: a systematic review and single-arm meta-analysis.

Biomedical engineering online
PURPOSE: The contouring of organs at risk (OARs) in head and neck cancer radiation treatment planning is a crucial, yet repetitive and time-consuming process. Recent studies have applied deep learning (DL) algorithms to automatically contour head and...

Image based prognosis in head and neck cancer using convolutional neural networks: a case study in reproducibility and optimization.

Scientific reports
In the past decade, there has been a sharp increase in publications describing applications of convolutional neural networks (CNNs) in medical image analysis. However, recent reviews have warned of the lack of reproducibility of most such studies, wh...

Deep learning for diagnosis of head and neck cancers through radiographic data: a systematic review and meta-analysis.

Oral radiology
PURPOSE: This study aims to review deep learning applications for detecting head and neck cancer (HNC) using magnetic resonance imaging (MRI) and radiographic data.

Technical note: Evaluation of deep learning based synthetic CTs clinical readiness for dose and NTCP driven head and neck adaptive proton therapy.

Medical physics
BACKGROUND: Adaptive proton therapy workflows rely on accurate imaging throughout the treatment course. Our centre currently utilizes weekly repeat CTs (rCTs) for treatment monitoring and plan adaptations. However, deep learning-based methods have re...

Contour subregion error detection methodology using deep learning auto-segmentation.

Medical physics
BACKGROUND: Inaccurate manual organ delineation is one of the high-risk failure modes in radiation treatment. Numerous automated contour quality assurance (QA) systems have been developed to assess contour acceptability; however, manual inspection of...

Consistency in contouring of organs at risk by artificial intelligence vs oncologists in head and neck cancer patients.

Acta oncologica (Stockholm, Sweden)
BACKGROUND: In the Danish Head and Neck Cancer Group (DAHANCA) 35 trial, patients are selected for proton treatment based on simulated reductions of Normal Tissue Complication Probability (NTCP) for proton compared to photon treatment at the referrin...

Prognostic significance of cyclin D1 expression pattern in HPV-negative oral and oropharyngeal carcinoma: A deep-learning approach.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
BACKGROUND: We aimed to establish image recognition and survival prediction models using a novel scoring system of cyclin D1 expression pattern in patients with human papillomavirus-negative oral or oropharyngeal squamous cell carcinoma.

A Novel Deep Learning Algorithm for Human Papillomavirus Infection Prediction in Head and Neck Cancers Using Routine Histology Images.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
The etiology of head and neck squamous cell carcinoma (HNSCC) involves multiple carcinogens, such as alcohol, tobacco, and infection with human papillomavirus (HPV). Because HPV infection influences the prognosis, treatment, and survival of patients ...

Geometric evaluations of CT and MRI based deep learning segmentation for brain OARs in radiotherapy.

Physics in medicine and biology
Deep-learning auto-contouring (DL-AC) promises standardisation of organ-at-risk (OAR) contouring, enhancing quality and improving efficiency in radiotherapy. No commercial models exist for OAR contouring based on brain magnetic resonance imaging (MRI...

Generation of synthetic CT from CBCT using deep learning approaches for head and neck cancer patients.

Biomedical physics & engineering express
To create a synthetic CT (sCT) from daily CBCT using either deep residual U-Net (DRUnet), or conditional generative adversarial network (cGAN) for adaptive radiotherapy planning (ART).First fraction CBCT and planning CT (pCT) were collected from 93 H...