AIMC Topic: Hematopoietic Stem Cell Transplantation

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Predicting Acute Graft-Versus-Host Disease Using Machine Learning and Longitudinal Vital Sign Data From Electronic Health Records.

JCO clinical cancer informatics Feb 1, 2020
PURPOSE: Acute graft-versus-host disease (aGVHD) remains a significant complication of allogeneic hematopoietic cell transplantation (HCT) and limits its broader application. The ability to predict grade II to IV aGVHD could potentially mitigate morb...
Electronic Health Records Female Retrospective Studies Adult Survival Rate Young Adult Aged Machine Learning Prognosis Biomarkers Humans Longitudinal Studies Follow-Up Studies ROC Curve Transplantation, Homologous Vital Signs Hematopoietic Stem Cell Transplantation Graft vs Host Disease Adolescent Infant Child Child, Preschool Male Middle Aged Hematologic Neoplasms
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Using a machine learning algorithm to predict acute graft-versus-host disease following allogeneic transplantation.

Blood advances Nov 26, 2019
Acute graft-versus-host disease (aGVHD) is 1 of the critical complications that often occurs following allogeneic hematopoietic stem cell transplantation (HSCT). Thus far, various types of prediction scores have been created using statistical calcula...
Hematologic Diseases Transplantation, Homologous Machine Learning Humans Prognosis Algorithms Area Under Curve Models, Theoretical Hematopoietic Stem Cell Transplantation Female Male Graft vs Host Disease Reproducibility of Results
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A BLSTM with Attention Network for Predicting Acute Myeloid Leukemia Patient's Prognosis using Comprehensive Clinical Parameters.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2019
The prognosis management is crucial for highrisk disease like Acute Myeloid Leukemia (AML) in order to support decisions of clinical treatment. However, the challenges of accurate and consistent forecasting lie in the high variability of the disease ...
Transplantation, Homologous Recurrence Hematopoietic Stem Cell Transplantation Retrospective Studies Neural Networks, Computer Leukemia, Myeloid, Acute Humans
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[Stability of high-dose etoposide dilutions for use in hematopoietic stem cell transplantation conditioning regimens].

Journal de pharmacie de Belgique Dec 1, 2015
High-dose etoposide is used in conditioning regimens for allogeneic stem cell transplantation. The limited stability of the drug induces barriers for its use for pharmacists, nurses and patients. When using a concentration of 10 mg/mL etoposide in ph...
Transplantation Conditioning Middle Aged Adult Topoisomerase II Inhibitors Male Hematopoietic Stem Cell Transplantation Etoposide Humans Drug Compounding
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