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Hippocampus

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An explainable artificial intelligence approach to spatial navigation based on hippocampal circuitry.

Neural networks : the official journal of the International Neural Network Society
Learning to navigate a complex environment is not a difficult task for a mammal. For example, finding the correct way to exit a maze following a sequence of cues, does not need a long training session. Just a single or a few runs through a new enviro...

Visual deep learning of unprocessed neuroimaging characterises dementia subtypes and generalises across non-stereotypic samples.

EBioMedicine
BACKGROUND: Dementia's diagnostic protocols are mostly based on standardised neuroimaging data collected in the Global North from homogeneous samples. In other non-stereotypical samples (participants with diverse admixture, genetics, demographics, MR...

HGM-cNet: Integrating hippocampal gray matter probability map into a cascaded deep learning framework improves hippocampus segmentation.

European journal of radiology
A robust cascaded deep learning framework with integrated hippocampal gray matter (HGM) probability map was developed to improve the hippocampus segmentation (called HGM-cNet) due to its significance in various neuropsychiatric disorders such as Alzh...

Neural learning rules for generating flexible predictions and computing the successor representation.

eLife
The predictive nature of the hippocampus is thought to be useful for memory-guided cognitive behaviors. Inspired by the reinforcement learning literature, this notion has been formalized as a predictive map called the successor representation (SR). T...

A comprehensive characterization of hippocampal feature ensemble serves as individualized brain signature for Alzheimer's disease: deep learning analysis in 3238 participants worldwide.

European radiology
OBJECTIVES: Hippocampal characterization is one of the most significant hallmarks of Alzheimer's disease (AD); rather, the single-level feature is insufficient. A comprehensive hippocampal characterization is pivotal for developing a well-performing ...

Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions.

Scientific reports
Hippocampal subregions differ in specialization and vulnerability to cell death. Neuron death and hippocampal atrophy have been a marker for the progression of Alzheimer's disease. Relatively few studies have examined neuronal loss in the human brain...

High-resolution CMOS-based biosensor for assessing hippocampal circuit dynamics in experience-dependent plasticity.

Biosensors & bioelectronics
Experiential richness creates tissue-level changes and synaptic plasticity as patterns emerge from rhythmic spatiotemporal activity of large interconnected neuronal assemblies. Despite numerous experimental and computational approaches at different s...

Exploring the Value of MRI Measurement of Hippocampal Volume for Predicting the Occurrence and Progression of Alzheimer's Disease Based on Artificial Intelligence Deep Learning Technology and Evidence-Based Medicine Meta-Analysis.

Journal of Alzheimer's disease : JAD
BACKGROUND: Alzheimer's disease (AD), a major dementia cause, lacks effective treatment. MRI-based hippocampal volume measurement using artificial intelligence offers new insights into early diagnosis and intervention in AD progression.

Deep learning-based, fully automated, pediatric brain segmentation.

Scientific reports
The purpose of this study was to demonstrate the performance of a fully automated, deep learning-based brain segmentation (DLS) method in healthy controls and in patients with neurodevelopmental disorders, SCN1A mutation, under eleven. The whole, cor...