AIMC Topic: HIV Infections

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Associations between weight gain, integrase inhibitors antiretroviral agents, and gut microbiome in people living with HIV: a cross-sectional study.

Scientific reports
Dolutegravir and bictegravir are second-generation HIV integrase strand transfer inhibitors (INSTIs) that were previously associated with abnormal weight gain. This monocentric cross-sectional study investigates associations between weight gain durin...

AI-driven analysis by identifying risk factors of VL relapse in HIV co-infected patients.

Scientific reports
Visceral Leishmaniasis (VL), also known as Kala-Azar, poses a significant global public health challenge and is a neglected disease, with relapses and treatment failures leading to increased morbidity and mortality. This study introduces an explainab...

Machine learning based gut microbiota pattern and response to fiber as a diagnostic tool for chronic inflammatory diseases.

BMC microbiology
Gut microbiota has been implicated in the pathogenesis of multiple gastrointestinal (GI) and systemic metabolic and inflammatory disorders where disrupted gut microbiota composition and function (dysbiosis) has been found in multiple studies. Thus, h...

The tumor microenvironment of non-small cell lung cancer impairs immune cell function in people with HIV.

The Journal of clinical investigation
Lung cancer is the leading cause of cancer mortality among people with HIV (PWH), with increased incidence and poor outcomes. This study explored whether the tumor microenvironment (TME) of HIV-associated non-small cell lung cancer (NSCLC) limits tum...

A Robust Cross-Platform Solution With the Sense2Quit System to Enhance Smoking Gesture Recognition: Model Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Smoking is a leading cause of preventable death, and people with HIV have higher smoking rates and are more likely to experience smoking-related health issues. The Sense2Quit study introduces innovative advancements in smoking cessation t...

Predictive survival modelings for HIV-related cryptococcosis: comparing machine learning approaches.

Frontiers in cellular and infection microbiology
INTRODUCTION: HIV-associated cryptococcosis is marked by unpredictable disease trajectories and persistently high mortality rates worldwide. Although improved risk stratification and tailored clinical management are urgently needed to enhance patient...

The future of HIV diagnostics: an exemplar in infectious diseases.

The lancet. HIV
Over the past 40 years, diagnostics have become the backbone of HIV prevention, treatment, and retention in care, and are central to the achievement of UNAIDS 95-95-95 targets. Over the next decade, the global HIV response will face difficult challen...

A comparative study on TB incidence and HIVTB coinfection using machine learning models on WHO global TB dataset.

Scientific reports
Tuberculosis, a deadly and contagious disease caused by Mycobacterium tuberculosis, remains a significant global public health threat. HIV co-infection significantly increases the risk of active TB recurrence and prolongs medical treatment for tuberc...

Systematic review of infodemiology studies using artificial intelligence: social media posts on HIV preexposure prophylaxis.

AIDS (London, England)
OBJECTIVES: To explore how artificial intelligence (AI) can enhance infodemiology, which distributes and scans information in the electronic medium, to process social media posts for HIV preexposure prophylaxis (PrEP).

Role of eccentricity based topological descriptors to predict anti-HIV drugs attributes with supervised machine learning algorithms.

Computers in biology and medicine
Chemical graphs are mathematical representations of molecular structures, where atoms are represented as vertices, while chemical bonds are depicted as edges of a graph. The chemical graphs are widely used in cheminformatics to analyze molecular prop...