BACKGROUND: Alexithymia, defined as difficulty identifying and describing one's emotions, has been identified as a transdiagnostic emotional process that impacts the course, severity, and treatment outcomes of psychiatric conditions such as posttraum...
BACKGROUND: In recent years, large language models (LLMs) have experienced rapid development. LLM-based virtual patients have begun to gain attention, offering new opportunities for simulations in medical education.
BACKGROUND: As data-driven medical research advances, vast amounts of medical data are being collected, giving researchers access to important information. However, issues such as heterogeneity, complexity, and incompleteness of datasets limit their ...
BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of preventable morbidity and mortality, highlighting the need for early risk stratification in primary prevention. Traditional Cox models assume proportional hazards and linear effects,...
An April 2025 survey of 118 first-year Japanese medical students found high use of generative artificial intelligence (84.7%) but limited formal learning (49.2%), with strong learning interest yet neutral assignment use, indicating a need for structu...
Systemic drug administration often causes off-target effects, limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We present a...
Chronic spontaneous urticaria (CSU) is an autoimmune prompted skin disorder, whose hallmarks include the unpredictable onset of hives and itch. Symptom duration typically exceed 6 weeks, and flares can occur for up to 5 years or longer if untreated, ...
Artificial intelligence (AI) is gradually transforming healthcare. However, despite its promised benefits, AI in healthcare also raises a number of ethical, legal and social concerns. Compliance by design (CbD) has been proposed as one way of address...
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Nov 13, 2025
Understanding consciousness remains a significant challenge in science. What distinguishes conscious beings from unconscious systems, such as organoids, artificial intelligence or other non-sentient entities? Research on consciousness often focuses o...
BACKGROUND: Vacuum-assisted breast biopsy (VABB) is a widely adopted minimally invasive technique for the diagnosis and treatment of breast lesions. However, the procedure heavily relies on real-time ultrasound guidance, posing significant challenges...
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