AIMC Topic: Humans

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[Possibilities of the utilization of trauma networks of the German Society for Trauma Surgery using digital solutions].

Unfallchirurgie (Heidelberg, Germany)
This paper describes the use of digital solutions to improve the care of trauma patients in Germany. The focus is on the trauma networks of the German Society for Trauma Surgery (Deutsche Gesellschaft für Unfallchirurgie, DGU). The use of digital sol...

Neuroscientific insights about computer vision models: a concise review.

Biological cybernetics
The development of biologically-inspired computational models has been the focus of study ever since the artificial neuron was introduced by McCulloch and Pitts in 1943. However, a scrutiny of literature reveals that most attempts to replicate the hi...

Spatially Informed Graph Structure Learning Extracts Insights from Spatial Transcriptomics.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Embeddings derived from cell graphs hold significant potential for exploring spatial transcriptomics (ST) datasets. Nevertheless, existing methodologies rely on a graph structure defined by spatial proximity, which inadequately represents the diversi...

Deep convolutional neural network-based identification and biological evaluation of MAO-B inhibitors.

International journal of biological macromolecules
Parkinson's disease (PD) is one of the most prominent motor disorder of adult-onset dementia connected to memory and other cognitive abilities. Individuals with this vicious neurodegenerative condition tend to have an elevated expression of Monoamine...

Learning to match patients to clinical trials using large language models.

Journal of biomedical informatics
OBJECTIVE: This study investigates the use of Large Language Models (LLMs) for matching patients to clinical trials (CTs) within an information retrieval pipeline. Our objective is to enhance the process of patient-trial matching by leveraging the se...

Identification of endocrine-disrupting chemicals targeting key OP-associated genes via bioinformatics and machine learning.

Ecotoxicology and environmental safety
Osteoporosis (OP), a metabolic disorder predominantly impacting postmenopausal women, has seen considerable progress in diagnosis and treatment over the past few decades. However, the intricate interplay between genetic factors and endocrine disrupto...

A Deep Learning System to Predict Epithelial Dysplasia in Oral Leukoplakia.

Journal of dental research
Oral leukoplakia (OL) has an inherent disposition to develop oral cancer. OL with epithelial dysplasia (OED) is significantly likely to undergo malignant transformation; however, routine OED assessment is invasive and challenging. This study investig...

Parameter optimization for stable clustering using FlowSOM: a case study from CyTOF.

Frontiers in immunology
High-dimensional cell phenotyping is a powerful tool to study molecular and cellular changes in health and diseases. CyTOF enables high-dimensional cell phenotyping using tens of surface and intra-cellular markers. To utilize the full potential of Cy...

Integrating whole genome sequencing and machine learning for predicting antimicrobial resistance in critical pathogens: a systematic review of antimicrobial susceptibility tests.

PeerJ
BACKGROUND: Infections caused by antibiotic-resistant bacteria pose a major challenge to modern healthcare. This systematic review evaluates the efficacy of machine learning (ML) approaches in predicting antimicrobial resistance (AMR) in critical pat...

Recommendations on the use of artificial intelligence in health promotion.

Progress in cardiovascular diseases
The purpose of this perspective is to provide recommendations on the use of Artificial Intelligence (AI) in health promotion. To arrive at these recommendations, we followed a 6-step process. The first step was to recruit an international authorship ...