AIMC Topic: Humans

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Machine learning identifies exosome related gene signatures for early prediction of non-small cell lung cancer.

Scientific reports
Non-small cell lung cancer (NSCLC) remains a major health challenge worldwide, mainly due to the lack of effective early diagnostic biomarkers. Exosome-related genes have recently emerged as potential diagnostic markers due to their roles in tumor pr...

Reducing annotation burden in physical activity research using vision language models.

Scientific reports
Data from wearable devices collected in free-living settings, and labelled with physical activity behaviours compatible with health research, are essential for both validating existing wearable-based measurement approaches and developing novel machin...

Privacy preservation in diabetic disease prediction using federated learning based on efficient cross stage recurrent model.

Scientific reports
Diabetic retinopathy (DR) is a major problemfor the diabetes patients that makes a serious threat to vision and causes the irreversible blindness if not diagnosed and treated early. Conventional deep learning-based approaches designed for DR detectio...

Smart defense based on explainable stacked machine learning architecture for securing internet of health things with K-means clustering.

Scientific reports
The Internet of Health Things (IoHT) transformed current healthcare by facilitating real-time patient monitoring and remote diagnosis via networked medical equipment. The advanced prevalence of interconnected medical devices creates substantial vulne...

PS3N: leveraging protein sequence-structure similarity for novel drug-drug interaction discovery.

Scientific reports
Adverse drug events represent a key challenge in public health, especially concerning drug safety profiling and drug surveillance. Drug-drug interactions represent one of the most popular types of adverse drug events. Most computational approaches to...

Multi-institutional validation of AI models for classifying urothelial neoplasms in digital pathology.

Scientific reports
This study proposes a deep learning approach for classifying normal, noninvasive, and invasive urothelial neoplasms via digitized histopathologicalimages. Despite many artificial intelligence (AI) models for cancer diagnosis, few focus on bladder les...

Long-term exposure to ambient air pollution and cardiometabolic multimorbidity in Chinese adults over 45 years.

Scientific reports
The rising prevalence of cardiometabolic multimorbidity (CMM), characterized by the coexistence of two or more cardiometabolic disorders, poses a significant public health challenge in aging populations. While ambient air pollution is a recognized en...

Non-linear interactions between intraocular, intracranial pressure and the retinal vascular pulse amplitude in the Fourier domain.

Scientific reports
The low explanatory power of a mixed effects linear model in evaluating interactions between retinal vascular pulse amplitude, intraocular pressure, and intracranial pressure suggests that these interactions are driven by non-linear dynamics. However...

Machine learning for early prediction of secondary cancer after radiotherapy.

Scientific reports
Secondary cancers (SCs) following radiotherapy (RT) represent a significant long-term risk of cancer survivors, necessitating accurate predictive models for early intervention. This study developed a machine learning (ML) model integrating clinical, ...

The impact of PANoptosis-related genes on immune profiles and subtype classification in ischemic stroke.

Scientific reports
Ischemic stroke (IS) is an acute neurological disorder causing brain dysfunction, with high mortality and disability. PANoptosis is a synchronized sort of regulated cell demise that combines the characteristics of pyroptosis, apoptosis, and necroptos...