AIMC Topic: Humans
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Integrating physiological signals for enhanced sleep apnea diagnosis with SleepNet.
Scientific reports
Aug 28, 2025
Sleep apnea, a prevalent respiratory disorder, poses significant health risks, including cardiovascular complications and behavioral issues, if left untreated. Traditional diagnostic methods like polysomnography, although effective, are often expensi...
A fused weighted federated learning-based adaptive approach for early-stage drug prediction.
Scientific reports
Aug 28, 2025
Early accurate drug prediction is crucial in clinical decision support, where privacy of the patient data is a paramount importance. In this study, we introduce a fused weighted adaptive federated learning (FWAFL) framework to achieve joint training ...
Diabetic retinal disease.
Nature reviews. Disease primers
Aug 28, 2025
Diabetic retinopathy is a complication of diabetes mellitus that is clinically characterized by changes in retinal microvasculature. Diabetic retinopathy is now better defined as diabetic retinal disease (DRD), as diabetes mellitus affects not only t...
Fire risk to structures in California's Wildland-Urban Interface.
Nature communications
Aug 28, 2025
The destructive impacts of wildfires on people, property and the environment have dramatically increased, especially in the Wildland-Urban Interface (WUI) in California. In these areas structures are threatened by both approaching flames and lofted e...
A comparative analysis of heterogeneity in lung cancer screening effectiveness in two randomised controlled trials.
Nature communications
Aug 28, 2025
Clinical trials demonstrate that screening can reduce lung cancer mortality by over 20%. However, lung cancer screening effectiveness (reduction in lung cancer specific mortality) may vary by personal risk-factors. Here we evaluate heterogeneity in l...
ROC Analysis of Biomarker Combinations in Fragile X Syndrome-Specific Clinical Trials: Evaluating Treatment Efficacy via Exploratory Biomarkers.
Translational psychiatry
Aug 28, 2025
Fragile X Syndrome (FXS) is a rare neurodevelopmental disorder caused by a trinucleotide repeat expansion on the 5' untranslated region of the FMR1 gene. FXS is characterized by intellectual disability, anxiety, sensory hypersensitivity, and difficul...
Foundation models in ophthalmology: a preliminary study on AI-assisted diagnosis of myopic maculopathy and posterior staphyloma using ultra-widefield fundus images.
BMJ open ophthalmology
Aug 28, 2025
OBJECTIVES: This study aims to detect characteristic fundus changes in pathological myopia using deep learning (DL)-based analysis of ultra-widefield (UWF) fundus imaging.
Understanding non-traditional caregivers: protocol for a scoping review of caregiver definitions, caregiver networks and outcome measures.
BMJ open
Aug 28, 2025
INTRODUCTION: Dementia caregiving is typically provided through a network of multiple individuals, particularly in diverse populations. Although family members of people living with Alzheimer's disease and Alzheimer's disease-related dementias, espec...
Evaluating the Feasibility of a Dyadic, Touch-Based Multimedia Tablet Intervention and Its Effects on the Caregiver-Patient Relationship Among Individuals With Mild Cognitive Impairment: Qualitative Triangulation Study.
JMIR aging
Aug 28, 2025
BACKGROUND: Approximately 20% of the global population is affected by mild cognitive impairment (MCI), with around 15% progressing to dementia within 2 years. Touch-based multimedia applications can support cognitive, social, and physical functioning...
Machine learning-based penetrance of genetic variants.
Science (New York, N.Y.)
Aug 28, 2025
Accurate variant penetrance estimation is crucial for precision medicine. We constructed machine learning (ML) models for 10 diseases using 1,347,298 participants with electronic health records, then applied them to an independent cohort with linked ...
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