Portal hypertension (PHT) is pivotal in managing decompensated cirrhosis. In clinical practice, hepatic venous collaterals are frequently present, often leading to failure or reduced accuracy of hepatic venous pressure gradient (HVPG) measurements, t...
Patient satisfaction is a crucial measure of healthcare quality, influencing both health outcomes and care experiences. This study aims to identify the factors influencing patient satisfaction in healthcare facilities using machine learning algorithm...
Non-invasive preoperative assessment of HER2 status is critical for identifying candidates for targeted therapy and personalizing treatment strategies in endometrial cancer (EC). This study aims to assess the preoperative value of multiparametric mag...
In silico drug-target interaction (DTI) prediction plays a key role in accelerating drug discovery and understanding molecular mechanisms. Traditional methods often struggle with the complexity and scale of biochemical data, thus limiting prediction ...
Signal transduction and targeted therapy
Oct 13, 2025
Nearly 30% of patients with schizophrenia respond inadequately to current antipsychotics, with unclear markers and mechanisms of antipsychotic efficacy. A total of 208 patients with schizophrenia treated for 6 weeks with oral paliperidone were analyz...
INTRODUCTION: There are many barriers to mental health services, including cost and stigma. Even when individuals receive professional care, assessments are intermittent and may be limited in part by the cyclical nature of psychiatric symptoms. The h...
BACKGROUND: Chronic obstructive pulmonary disease (COPD) remains a leading global health burden. In primary care, the inconsistent availability of spirometry and symptom scores limits the detection of patients with poor disease control. There is a pr...
The use of big data and machine learning has been discussed in an expanding literature, detailing concerns on ethical issues and societal implications. In this paper we focus on big data and machine learning in the context of health systems and with ...
PURPOSE: Obstructive sleep apnea (OSA) is highly prevalent among obese individuals, with a complex and bidirectional relationship wherein obesity not only serves as a primary risk factor for OSA but also exacerbates its severity. This interconnection...
A significant amount of scholarship and funding has been dedicated to ethical and social studies of new and emerging science and technology (NEST), from nanotechnology to synthetic biology, and Artificial Intelligence. Quantum technologies comprise t...
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