AIMC Topic: Humans

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Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.

Nature communications
A promise of genomics in precision medicine is to provide individualized genetic risk predictions. Polygenic risk scores (PRS), computed by aggregating effects from many genomic variants, have been developed as a useful tool in complex disease resear...

NanoCaller for accurate detection of SNPs and indels in difficult-to-map regions from long-read sequencing by haplotype-aware deep neural networks.

Genome biology
Long-read sequencing enables variant detection in genomic regions that are considered difficult-to-map by short-read sequencing. To fully exploit the benefits of longer reads, here we present a deep learning method NanoCaller, which detects SNPs usin...

Multi-parametric MRI phenotype with trustworthy machine learning for differentiating CNS demyelinating diseases.

Journal of translational medicine
BACKGROUND: Misdiagnosis of multiple sclerosis (MS) and neuromyelitis optica (NMO) may delay the treatment, resulting in poor prognosis. However, the precise identification of these two diseases is still challenging in clinical practice. We aimed to ...

Robotic devices for paediatric rehabilitation: a review of design features.

Biomedical engineering online
Children with physical disabilities often have limited performance in daily activities, hindering their physical development, social development and mental health. Therefore, rehabilitation is essential to mitigate the adverse effects of the differen...

ParaMed: a parallel corpus for English-Chinese translation in the biomedical domain.

BMC medical informatics and decision making
BACKGROUND: Biomedical language translation requires multi-lingual fluency as well as relevant domain knowledge. Such requirements make it challenging to train qualified translators and costly to generate high-quality translations. Machine translatio...

Applying a novel approach to scoping review incorporating artificial intelligence: mapping the natural history of gonorrhoea.

BMC medical research methodology
BACKGROUND: Systematic and scoping literature searches are increasingly resource intensive. We present the results of a scoping review which combines the use of a novel artificial-intelligence-(AI)-assisted Medline search tool with two other 'traditi...

Influential Usage of Big Data and Artificial Intelligence in Healthcare.

Computational and mathematical methods in medicine
Artificial intelligence (AI) is making computer systems capable of executing human brain tasks in many fields in all aspects of daily life. The enhancement in information and communications technology (ICT) has indisputably improved the quality of pe...

Comparison of two deep learning image reconstruction algorithms in chest CT images: A task-based image quality assessment on phantom data.

Diagnostic and interventional imaging
PURPOSE: The purpose of this study was to compare the effect of two deep learning image reconstruction (DLR) algorithms in chest computed tomography (CT) with different clinical indications.

The evolution of image guidance in robotic-assisted laparoscopic prostatectomy (RALP): a glimpse into the future.

Journal of robotic surgery
OBJECTIVES: To describe the innovative intraoperative technologies emerging to aid surgeons during minimally invasive robotic-assisted laparoscopic prostatectomy.