Despite recent advances in cancer treatment, developing better therapeutic reagents remains an essential task for oncologists. To accurately characterize drug efficacy, 3D cell culture holds great promise as opposed to conventional 2D monolayer cultu...
BACKGROUND: Although the mouse is widely used to model human lung development, function, and disease, our understanding of the molecular mechanisms involved in alveolarization of the peripheral lung is incomplete. Recently, the Molecular Atlas of Lun...
Chinese journal of integrative medicine
Oct 24, 2019
As an interdisciplinary subject of medicine and artificial intelligence, intelligent diagnosis and treatment has received extensive attention. The standardization of Chinese medicine (CM) diagnosis has been always a bottleneck in the modernization an...
Triple-negative breast cancer (TNBC), colon adenocarcinoma (COAD), ovarian cancer (OV), and glioblastoma multiforme (GBM) are common malignant tumors, in which significant challenges are still faced in early diagnosis, treatment, and prognosis. There...
IEEE journal of biomedical and health informatics
Oct 23, 2019
Despite the potential to revolutionise disease diagnosis by performing data-driven classification, clinical interpretability of ConvNet remains challenging. In this paper, a novel clinical interpretable ConvNet architecture is proposed not only for a...
Generalized nucleus segmentation techniques can contribute greatly to reducing the time to develop and validate visual biomarkers for new digital pathology datasets. We summarize the results of MoNuSeg 2018 Challenge whose objective was to develop ge...
Computer methods and programs in biomedicine
Oct 23, 2019
BACKGROUND AND OBJECTIVES: Malignant lymphomas are cancers of the immune system and are characterized by enlarged lymph nodes that typically spread across many different sites. Many different histological subtypes exist, whose diagnosis is typically ...
Toxicologic pathology is transitioning from analog to digital methods. This transition seems inevitable due to a host of ongoing social and medical technological forces. Of these, artificial intelligence (AI) and in particular machine learning (ML) a...
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