Humans

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2D-EM clustering approach for high-dimensional data through folding feature vectors.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Clustering methods are becoming widely utilized in biomedical research where the volume and complexity of data is rapidly increasing. Unsupervised clustering of patient information can reveal distinct phenotype groups with different under...
Cluster Analysis Humans Algorithms Transcriptome
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Divisive hierarchical maximum likelihood clustering.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Biological data comprises various topologies or a mixture of forms, which makes its analysis extremely complicated. With this data increasing in a daily basis, the design and development of efficient and accurate statistical methods has b...
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Cluster Analysis Humans Probability Algorithms
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Deep learning architectures for multi-label classification of intelligent health risk prediction.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Multi-label classification of data remains to be a challenging problem. Because of the complexity of the data, it is sometimes difficult to infer information about classes that are not mutually exclusive. For medical data, patients could ...
Support Vector Machine Chronic Disease Health Risk Assessment Deep Learning ROC Curve Neural Networks, Computer Algorithms Humans
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Effective computational detection of piRNAs using n-gram models and support vector machine.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Piwi-interacting RNAs (piRNAs) are a new class of small non-coding RNAs that are known to be associated with RNA silencing. The piRNAs play an important role in protecting the genome from invasive transposons in the germline. Recent studi...
Area Under Curve RNA, Small Interfering Humans Animals ROC Curve Computational Biology Support Vector Machine Databases, Genetic
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Automated classification and characterization of the mitotic spindle following knockdown of a mitosis-related protein.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Cell division (mitosis) results in the equal segregation of chromosomes between two daughter cells. The mitotic spindle plays a pivotal role in chromosome alignment and segregation during metaphase and anaphase. Structural or functional e...
Humans Mitosis Spindle Apparatus
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ALE: automated label extraction from GEO metadata.

BMC bioinformatics Dec 28, 2017
BACKGROUND: NCBI's Gene Expression Omnibus (GEO) is a rich community resource containing millions of gene expression experiments from human, mouse, rat, and other model organisms. However, information about each experiment (metadata) is in the format...
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Animals Male Middle Aged Machine Learning Algorithms Female Gene Expression Metadata Automation Reference Standards Rats Databases, Genetic Age Factors Humans Molecular Sequence Annotation Gene Ontology
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Development of models for predicting Torsade de Pointes cardiac arrhythmias using perceptron neural networks.

BMC bioinformatics Dec 28, 2017
BACKGROUND: Blockage of some ion channels and in particular, the hERG (human Ether-a'-go-go-Related Gene) cardiac potassium channel delays cardiac repolarization and can induce arrhythmia. In some cases it leads to a potentially life-threatening arrh...
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Neural Networks, Computer Male Middle Aged Humans Heart Ventricles Long QT Syndrome Arrhythmias, Cardiac Myocytes, Cardiac ROC Curve Electrocardiography Action Potentials Models, Cardiovascular Ether-A-Go-Go Potassium Channels Torsades de Pointes
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Automatic Classification of Sub-Techniques in Classical Cross-Country Skiing Using a Machine Learning Algorithm on Micro-Sensor Data.

Sensors (Basel, Switzerland) Dec 28, 2017
The automatic classification of sub-techniques in classical cross-country skiing provides unique possibilities for analyzing the biomechanical aspects of outdoor skiing. This is currently possible due to the miniaturization and flexibility of wearabl...
Athletes Skiing Machine Learning Algorithms Biomechanical Phenomena Humans
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Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks.

International journal of molecular sciences Dec 28, 2017
Maternal obesity has been related to adverse neonatal outcomes and fetal programming. Oxidative stress and adipokines are potential biomarkers in such pregnancies; thus, the measurement of these molecules has been considered critical. Therefore, we d...
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DNA Gene Expression 8-Hydroxy-2'-Deoxyguanosine Body Mass Index Age Factors Obesity Gestational Age Resistin Pregnancy Trimester, Third Deoxyguanosine Protein Carbonylation Leptin Adiponectin Pregnancy Female Adult Oxidative Stress Malondialdehyde Severity of Illness Index Case-Control Studies Humans Neural Networks, Computer Biomarkers
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Risk factors for predicting increased surgical drain output in patients after anterior cervical corpectomy and fusion.

Journal of orthopaedic surgery and research Dec 28, 2017
BACKGROUND: Although measures to reduce and treat the postoperative surgical drain output are discussed, along with the increased interest in causative factors related to the prevention and treatment reported by many studies, these are still controve...
Humans Risk Factors Aged Retrospective Studies Female Predictive Value of Tests Postoperative Complications Cervical Vertebrae Cohort Studies Diskectomy Spinal Fusion Drainage Adult Male Middle Aged
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