AIMC Topic: Humans

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Prediction of recurrence after surgery for pituitary adenoma using machine learning- based models: systematic review and meta-analysis.

BMC endocrine disorders Jul 1, 2025
BACKGROUND: Predicting pituitary adenoma (PA) recurrence after surgical resection is critical for guiding clinical decision-making, and machine learning (ML) based models show great promise in improving the accuracy of these predictions. These models...
Pituitary Neoplasms Humans Adenoma Machine Learning Neoplasm Recurrence, Local Prognosis
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Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner.

BMC medicine Jul 1, 2025
BACKGROUND: In humans, uric acid is a product of purine metabolism that impacts the vascular system. In addition to effects on arterial vascular tone, associations between serum uric acid concentrations-even in the physiological range-and arterial hy...
Sex Factors Germany Vascular Stiffness Pulse Wave Analysis Uric Acid Humans Female Adult Male Aged Cross-Sectional Studies Middle Aged
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Can mutation abundance assess the biological behavior of BRAF-positive papillary thyroid carcinoma?

Journal of translational medicine Jul 1, 2025
BACKGROUND: BRAF mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Nevertheless, the association between BRAF mutation status and abundance and the biological behavior of PTC is unclear. Thus, this study investigated wh...
Thyroid Cancer, Papillary Proto-Oncogene Proteins B-raf Mutation Humans Retrospective Studies Biopsy, Fine-Needle Male Female Amino Acid Substitution Middle Aged Aged Thyroid Neoplasms Adult ROC Curve
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Deep learning-based dipeptidyl peptidase IV inhibitor screening, experimental validation, and GaMD/LiGaMD analysis.

BMC biology Jul 1, 2025
BACKGROUND: Dipeptidyl peptidase-4 (DPP4) is considered a crucial enzyme in type 2 diabetes (T2D) treatment, targeted by inhibitors due to its role in cleaving glucagon-like peptide-1 (GLP-1). In this study, a novel DPP4 inhibitor screening strategy ...
Deep Learning Diabetes Mellitus, Type 2 Molecular Dynamics Simulation Dipeptidyl Peptidase 4 Dipeptidyl-Peptidase IV Inhibitors Drug Evaluation, Preclinical Ligands Humans Molecular Docking Simulation
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Exploring the possibilities and limitations of customized large language model to support and improve cervical cancer screening.

BMC medical informatics and decision making Jul 1, 2025
BACKGROUND: The rapid advancement of artificial intelligence, driven by Generative Pre-trained Transformers (GPT), has transformed natural language processing. Prompt engineering plays a key role in guiding model outputs effectively. Our primary obje...
Natural Language Processing Adult Patient Education as Topic Uterine Cervical Neoplasms Large Language Models Middle Aged Humans Early Detection of Cancer Artificial Intelligence Female
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Attention-driven hybrid deep learning and SVM model for early Alzheimer's diagnosis using neuroimaging fusion.

BMC medical informatics and decision making Jul 1, 2025
Alzheimer's Disease (AD) poses a significant global health challenge, necessitating early and accurate diagnosis to enable timely interventions. AD is a progressive neurodegenerative disorder that affects millions worldwide and is one of the leading ...
Alzheimer Disease Early Diagnosis Neuroimaging Deep Learning Support Vector Machine Humans Aged
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The value of machine learning based on spectral CT quantitative parameters in the distinguishing benign from malignant thyroid micro-nodules.

BMC cancer Jul 1, 2025
BACKGROUND AND AIMS: More cases of thyroid micro-nodules have been diagnosed annually in recent years because of advancements in diagnostic technologies and increased public health awareness. To explore the application value of various machine learni...
Bayes Theorem ROC Curve Support Vector Machine Diagnosis, Differential Female Aged Adult Thyroid Neoplasms Thyroid Nodule Male Middle Aged Humans Machine Learning Algorithms Tomography, X-Ray Computed
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Plasma Lyso-PE 22:6 and Lyso-PE 20:4 are associated with development of mild to moderate depression revealed by metabolomics: a pilot study.

BMC psychiatry Jul 1, 2025
BACKGROUND: Mild to moderate depression (MMD), as an early stage of depression, has a high incidence and may progress to severe depression, even leading to suicide. The lack of effective screening and treatment is due to the unknown metabolic changes...
Humans Machine Learning Biomarkers Middle Aged Case-Control Studies Depression Pilot Projects Female Adult Male Lysophospholipids Metabolomics Chromatography, High Pressure Liquid
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Student perceptions of GenAI as a virtual tutor to support collaborative research training for health professionals.

BMC medical education Jul 1, 2025
BACKGROUND: Research and evaluation skills are essential in healthcare education. Instructors frequently employ collaborative learning models to teach these competencies; however, delivering timely and personalized feedback to multiple groups can be ...
Male Surveys and Questionnaires Cooperative Behavior Humans Formative Feedback Female Health Personnel Students, Medical
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Preoperative MRI-based deep learning reconstruction and classification model for assessing rectal cancer.

BMC medical imaging Jul 1, 2025
BACKGROUND: To determine whether deep learning reconstruction (DLR) could improve the image quality of rectal MR images, and to explore the discrimination of the TN stage of rectal cancer by different readers and deep learning classification models, ...
Male Middle Aged Deep Learning ROC Curve Retrospective Studies Signal-To-Noise Ratio Image Processing, Computer-Assisted Rectal Neoplasms Humans Aged Female Magnetic Resonance Imaging Diffusion Magnetic Resonance Imaging Aged, 80 and over Image Interpretation, Computer-Assisted Neoplasm Staging Adult
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