AIMC Topic: Humans

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Online machine learning model for predicting delirium risk in elderly patients with chronic kidney disease: development and preliminary validation.

European journal of medical research
BACKGROUND: Delirium frequently complicates elderly chronic kidney disease (CKD) patients due to multifactorial vulnerability. Early detection in geriatric intensive care unit (ICU) settings is challenged by traditional assessments' communication def...

Knowledge-level comparison in pulpal and periapical diseases: dental students versus artificial intelligence models (Gemini, Microsoft Copilot, ChatGPT-3.5, ChatGPT-4o): cross-sectional study.

BMC medical education
BACKGROUND: This study explored the diagnostic accuracy of artificial intelligence (AI) chatbots and dental students when responding to questions related to pulpal and periapical diseases. Rapid advancements in AI have led to increased interest in th...

Construction of a novel 3-gene diagnostic signature related to senescence in intervertebral disc degeneration.

European journal of medical research
BACKGROUND: Numerous studies have manifested that cellular senescence involves in the pathogenesis of intervertebral disc degeneration (IDD). Here, we constructed a novel senescence-related genes (SRGs) signature for IDD.

The relationship between amyloid-β peptide spectrum and the spastic paraparesis phenotype in autosomal dominant Alzheimer's disease.

Alzheimer's research & therapy
BACKGROUND: More than 300 mutations in presenilin 1 (PSEN1) lead to autosomal dominant Alzheimer's disease (ADAD). PSEN1, as the catalytic subunit of γ-secretase, generates amyloid-β (Aβ) peptides through a sequential proteolysis of the amyloid precu...

A research roadmap for AI opportunities in student assessment for medical education.

BMC medical education
The integration of Artificial Intelligence (AI) in medical education is rapidly transforming assessment practices, offering unprecedented opportunities to enhance student evaluation, feedback, and learning pathways. However, despite the potential, a ...

Comparison of 2D, 2.5D, and 3D landmark localization networks for 3D cephalometry in CT images.

BMC oral health
BACKGROUND: Accurate landmark localization is important for three-dimensional (3D) cephalometric analysis. Although deep learning has shown promising performance for 3D landmark localization, the high computational burden of processing volumetric dat...

Interpretable and reproducible machine learning model for coronary calcification and segment-level stenoses stratification on computed tomography angiography.

BMC medicine
BACKGROUND: Coronary computed tomography angiography (CCTA) is widely used as a first-line tool for diagnosing and managing coronary artery disease (CAD), and machine learning (ML)-based analysis shows promise for quantitative CAD assessment.

An interpretable geometric graph neural network for enhancing the generalizability of drug-target interaction prediction.

BMC biology
BACKGROUND: Accurate prediction of drug-target interactions (DTIs) is essential for advancing drug discovery. Although numerous computational methods have been proposed, many exhibit limited generalization, particularly when dealing with unseen drugs...

Human-centered AI in healthcare: empowering patients and support persons in clinical decision-making.

BMC medical informatics and decision making
Artificial intelligence (AI) has emerged as a promising tool to enhance medical practice and improve patient outcomes. However, introducing AI in interactions between patients, support persons (SPs) and physicians may create real or perceived informa...

Early detection of at-risk health sciences students: a machine learning-based predictive study using midterm grades.

BMC medical education
BACKGROUND: Early identification of students at academic risk is critical in health sciences education, particularly in regions prioritizing healthcare workforce development. This study evaluated the application of established machine learning (ML) c...