AIMC Topic: Hydrocortisone

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Effect of congenital adrenal hyperplasia treated by glucocorticoids on plasma metabolome: a machine-learning-based analysis.

Scientific reports
BACKGROUND: Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency leads to impaired cortisol biosynthesis. Treatment includes glucocorticoid supplementation. We studied the specific metabolomics signatures in CAH patients using two di...

Road Transport of Late-Pregnant Mares Advances the Onset of Foaling.

Journal of equine veterinary science
Cortisol is involved in the initiation of parturition and we hypothesized that increased maternal cortisol release advances the onset of foaling. Transport is a stressor for horses and induces an increase in cortisol release. To determine stress effe...

Computational modeling of the monoaminergic neurotransmitter and male neuroendocrine systems in an analysis of therapeutic neuroadaptation to chronic antidepressant.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Second-line depression treatment involves augmentation with one (rarely two) additional drugs, of chronic administration of a selective serotonin reuptake inhibitor (SSRI), which is the first-line depression treatment. Unfortunately, many depressed p...

Artificial Intelligence based facial recognition for Mood Charting among men on life style modification and it's correlation with cortisol.

Asian journal of psychiatry
UNLABELLED: Today, clinicians and researchers believe that mood disorders in children and adolescents remain one of the most under diagnosed mental health problems. Mood disorders in adolescents also put them at risk for other conditions that may per...

Job interview training targeting nonverbal communication using an android robot for individuals with autism spectrum disorder.

Autism : the international journal of research and practice
Job interviews are significant barriers for individuals with autism spectrum disorder because these individuals lack good nonverbal communication skills. We developed a job interview training program using an android robot. The job interview training...

Refractory collapse and severe burn: Think about acute adrenal insufficiency.

The American journal of emergency medicine
INTRODUCTION: Adrenal insufficiency (AI) is a rare endocrine disorder, which can in its acute form be life-threatening in case of late diagnosis or treatment. The stress during a thermal burn can easily decompensate the AI. We report the case of an a...

Increased Cardiovascular Risk in Patients with Adrenal Insufficiency: A Short Review.

BioMed research international
Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (AI) and increased cardiovascular risk (CVR). Patients with AI receive glucocorticoid (GC) replacement...

Cardiovascular events in patients with mild autonomous cortisol secretion: analysis with artificial neural networks.

European journal of endocrinology
BACKGROUND: The independent role of mild autonomous cortisol secretion (ACS) in influencing the cardiovascular event (CVE) occurrence is a topic of interest. We investigated the role of mild ACS in the CVE occurrence in patients with adrenal incident...