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Hydrogen-Ion Concentration

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Artificial neural network associated to UV/Vis spectroscopy for monitoring bioreactions in biopharmaceutical processes.

Bioprocess and biosystems engineering
Currently, mammalian cells are the most utilized hosts for biopharmaceutical production. The culture media for these cell lines include commonly in their composition a pH indicator. Spectroscopic techniques are used for biopharmaceutical process moni...

Comparison of ultrasonic with stirrer performance for removal of sunset yellow (SY) by activated carbon prepared from wood of orange tree: artificial neural network modeling.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The present work focused on the removal of sunset yellow (SY) dye from aqueous solution by ultrasound-assisted adsorption and stirrer by activated carbon prepared from wood of an orange tree. Also, the artificial neural network (ANN) model was used f...

Experimental analysis and mathematical prediction of Cd(II) removal by biosorption using support vector machines and genetic algorithms.

New biotechnology
We investigated the bioremoval of Cd(II) in batch mode, using dead and living biomass of Trichoderma viride. Kinetic studies revealed three distinct stages of the biosorption process. The pseudo-second order model and the Langmuir model described wel...

Artificial neural network (ANN) method for modeling of sunset yellow dye adsorption using zinc oxide nanorods loaded on activated carbon: Kinetic and isotherm study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In this research, ZnO nanoparticle loaded on activated carbon (ZnO-NPs-AC) was synthesized simply by a low cost and nontoxic procedure. The characterization and identification have been completed by different techniques such as SEM and XRD analysis. ...

Seq2Topt: a sequence-based deep learning predictor of enzyme optimal temperature.

Briefings in bioinformatics
An accurate deep learning predictor is needed for enzyme optimal temperature (${T}_{opt}$), which quantitatively describes how temperature affects the enzyme catalytic activity. In comparison with existing models, a new model developed in this study,...

[AcidBasePred: a protein acid-base tolerance prediction platform based on deep learning].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
The structures and activities of enzymes are influenced by pH of the environment. Understanding and distinguishing the adaptation mechanisms of enzymes to extreme pH values is of great significance for elucidating the molecular mechanisms and promoti...

Optimization of metronidazole SR buccal tablet for gingivitis using genetic algorithm.

Pakistan journal of pharmaceutical sciences
Gingivitis is a condition that needs sustained concentration of antibiotic locally over extended period of time. The current study aimed to formulate and evaluate the sustained and localized release of metronidazole (MTZ) as mucoadhesive buccal table...

[Determination of tranexamic acid in essential cosmetics by pre-column derivatization capillary electrophoresis coupled with electrogenerated chemiluminescence detection].

Se pu = Chinese journal of chromatography
-Methylation of tranexamic acid yields an unique derivative, which generates strong co-luminescence signals in the presence of an electrochemiluminescence reagent such as Ru(bpy). Using this principle, we established a highly selective analytical met...

Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol.

Acta pharmaceutica (Zagreb, Croatia)
The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution,...

Synthesis of MnFeO and MnO magnetic nano-composites with enhanced properties for adsorption of Cr(VI): artificial neural network modeling.

Water science and technology : a journal of the International Association on Water Pollution Research
This study reports adsorptive removal of Cr(VI) by magnetic manganese ferrite and manganese oxide nano-particles (MnF-MO-NPs) composite from aqueous media. The X-ray diffraction pattern of MnF-MO-NPs revealed a polycrystalline nature with nanoscale c...