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Hydrolysis

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Design, preparation and characterization of pH-responsive prodrug micelles with hydrolyzable anhydride linkages for controlled drug delivery.

Journal of colloid and interface science
We report a new prodrug micelle-based approach in which a model hydrophobic non-steroidal anti-inflammatory drug (NSAID), ibuprofen (Ibu), is tethered to amphiphilic methoxy polyethylene glycol-polypropylene fumarate (mPEG-PPF) diblock copolymer via ...

Synthesis of Water-Soluble Imidazolium Polyesters as Potential Nonviral Gene Delivery Vehicles.

Biomacromolecules
The inherent hydrolytic reactivity of polyesters renders them excellent candidates for a variety of biomedical applications. Incorporating ionic groups further expands their potential impact, encompassing charge-dependent function such as deoxyribonu...

Controlled surface morphology and hydrophilicity of polycaprolactone toward human retinal pigment epithelium cells.

Materials science & engineering. C, Materials for biological applications
Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of the treatment of retina diseases such as age-related macular degeneration (AMD) which deteriorating photoreceptors and finally happening blindness. In this s...

Chromatographic Study of Azintamide in Bulk Powder and in Pharmaceutical Formulation in the Presence of Its Degradation Form.

Journal of AOAC International
Two specific, sensitive, and precise stability-indicating chromatographic methods were developed, optimized, and validated for the determination of Azintamide (AZ) in the presence of its degradation product. The first method was TLC combined with the...

Polydopamine-assisted partial hydrolyzed poly(2-methyl-2-oxazolinze) as coating for determination of melamine in milk by capillary electrophoresis.

Talanta
Nitrogen-rich melamine (66% by mass) had been found to be illegally adulterated to milk products and animal feed in order to increase the apparent protein content, and ingestion of melamine may lead to the formation of kidney stones. Hence, the devel...

Prediction of sugar yields during hydrolysis of lignocellulosic biomass using artificial neural network modeling.

Bioresource technology
The present investigation was carried out to study application of ANN as a tool for predicting sugar yields of pretreated biomass during hydrolysis process at various time intervals. Since it is known that biomass loading and particle size influences...

Encoder-decoder neural networks for predicting future FTIR spectra - application to enzymatic protein hydrolysis.

Journal of biophotonics
In the process of converting food-processing by-products to value-added ingredients, fine grained control of the raw materials, enzymes and process conditions ensures the best possible yield and economic return. However, when raw material batches lac...

Machine learning-aided engineering of hydrolases for PET depolymerization.

Nature
Plastic waste poses an ecological challenge and enzymatic degradation offers one, potentially green and scalable, route for polyesters waste recycling. Poly(ethylene terephthalate) (PET) accounts for 12% of global solid waste, and a circular carbon e...

[Separation and screening of antioxidant peptides from based on nano flow liquid chromatography].

Se pu = Chinese journal of chromatography
As a rich source of high activity antioxidant peptides, is a key marine natural product with a high processing value. Due to the high complexity of fish tissues, high recovery extraction and high efficiency screening of the active antioxidant peptid...

Use of artificial neuronal networks for prediction of the control parameters in the process of anaerobic digestion with thermal pretreatment.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
This article focuses on the analysis of the behavior patterns of the variables involved in the anaerobic digestion process. The objective is to predict the impact factor and the behavior pattern of the variables, i.e., temperature, pH, volatile solid...