AIMC Topic: Immune Checkpoint Proteins

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Development of a MVI associated HCC prognostic model through single cell transcriptomic analysis and 101 machine learning algorithms.

Scientific reports Mar 7, 2025
Hepatocellular carcinoma (HCC) is an exceedingly aggressive form of cancer that often carries a poor prognosis, especially when it is complicated by the presence of microvascular invasion (MVI). Identifying patients at high risk of MVI is crucial for...
Humans Prognosis Clinical Decision-Making Machine Learning Precision Medicine Meta-Analysis as Topic Mutation Neoplasm Invasiveness Liver Microvessels Immune Checkpoint Proteins Datasets as Topic Kaplan-Meier Estimate Single-Cell Gene Expression Analysis Immunotherapy Gene Expression Regulation, Neoplastic Treatment Outcome Liver Neoplasms Carcinoma, Hepatocellular Biomarkers, Tumor Risk Assessment
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Prognostic model incorporating immune checkpoint genes to predict the immunotherapy efficacy for lung adenocarcinoma: a cohort study integrating machine learning algorithms.

Immunologic research May 16, 2024
This study aimed to develop and validate a nomogram based on immune checkpoint genes (ICGs) for predicting prognosis and immune checkpoint blockade (ICB) efficacy in lung adenocarcinoma (LUAD) patients. A total of 385 LUAD patients from the TCGA data...
Immune Checkpoint Proteins Treatment Outcome Adenocarcinoma of Lung Immune Checkpoint Inhibitors Lung Neoplasms Immunotherapy Nomograms Middle Aged Cohort Studies Male Algorithms Female Prognosis Biomarkers, Tumor Humans Machine Learning
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A Machine Learning Approach Yields a Multiparameter Prognostic Marker in Liver Cancer.

Cancer immunology research Jan 11, 2021
A number of staging systems have been developed to predict clinical outcomes in hepatocellular carcinoma (HCC). However, no general consensus has been reached regarding the optimal model. New approaches such as machine learning (ML) strategies are po...
Hepatectomy Portal Vein Male Lymphocyte Count Middle Aged Kaplan-Meier Estimate Retrospective Studies Adult Female Liver Venous Thrombosis T-Lymphocytes Models, Immunological Risk Factors Neoplasm Staging Neoplasm Invasiveness Liver Neoplasms Risk Assessment Immune Checkpoint Proteins Young Adult Humans Carcinoma, Hepatocellular Adolescent Machine Learning Prognosis
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