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Immune Checkpoint Proteins

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A Machine Learning Approach Yields a Multiparameter Prognostic Marker in Liver Cancer.

Cancer immunology research 33431375
A number of staging systems have been developed to predict clinical outcomes in hepatocellular carcinoma (HCC). However, no general consensus has been reached regarding the optimal model. New approaches such as machine learning (ML) strategies are po...
Adolescent Adult Carcinoma, Hepatocellular Female Hepatectomy Humans Immune Checkpoint Proteins Kaplan-Meier Estimate Liver Liver Neoplasms Lymphocyte Count Machine Learning Male Middle Aged Models, Immunological Neoplasm Invasiveness Neoplasm Staging Portal Vein Prognosis Retrospective Studies Risk Assessment Risk Factors T-Lymphocytes Venous Thrombosis Young Adult
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Prognostic model incorporating immune checkpoint genes to predict the immunotherapy efficacy for lung adenocarcinoma: a cohort study integrating machine learning algorithms.

Immunologic research 38755433
This study aimed to develop and validate a nomogram based on immune checkpoint genes (ICGs) for predicting prognosis and immune checkpoint blockade (ICB) efficacy in lung adenocarcinoma (LUAD) patients. A total of 385 LUAD patients from the TCGA data...
Adenocarcinoma of Lung Algorithms Biomarkers, Tumor Cohort Studies Female Humans Immune Checkpoint Inhibitors Immune Checkpoint Proteins Immunotherapy Lung Neoplasms Machine Learning Male Middle Aged Nomograms Prognosis Treatment Outcome
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Development of a MVI associated HCC prognostic model through single cell transcriptomic analysis and 101 machine learning algorithms.

Scientific reports 40055377
Hepatocellular carcinoma (HCC) is an exceedingly aggressive form of cancer that often carries a poor prognosis, especially when it is complicated by the presence of microvascular invasion (MVI). Identifying patients at high risk of MVI is crucial for...
Biomarkers, Tumor Carcinoma, Hepatocellular Clinical Decision-Making Datasets as Topic Gene Expression Regulation, Neoplastic Humans Immune Checkpoint Proteins Immunotherapy Kaplan-Meier Estimate Liver Liver Neoplasms Machine Learning Meta-Analysis as Topic Microvessels Mutation Neoplasm Invasiveness Precision Medicine Prognosis Risk Assessment Single-Cell Gene Expression Analysis Treatment Outcome
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