AIMC Topic: Injections
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PLGA-based long-acting injectable (LAI) formulations.
Journal of controlled release : official journal of the Controlled Release Society
Apr 21, 2025
Long-acting injectable (LAI) formulations, which deliver drugs over weeks or months, have been in use for more than three decades. Most clinically approved LAI products are formulated using poly(lactide-co-glycolide) (PLGA) polymers. Historically, th...
Application of an AI-Based Model for Non-Invasive Sonographic Assessment for Injection Laryngoplasty.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Mar 21, 2025
OBJECTIVE: Hyaluronic acid (HA) can be degraded over time. However, the persistence of the effects after injection laryngoplasty (IL) for unilateral vocal fold paralysis (UVFP) has been observed. The relation between HA residue and clinical voice out...
ARViS: a bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset cerebral cortex.
Nature communications
Sep 10, 2024
Genetically encoded fluorescent sensors continue to be developed and improved. If they could be expressed across multiple cortical areas in non-human primates, it would be possible to measure a variety of spatiotemporal dynamics of primate-specific c...
Analysis on key parameters in subretinal injection facilitating a predictable and automated robot-assisted treatment in gene therapy.
The international journal of medical robotics + computer assisted surgery : MRCAS
Aug 16, 2023
BACKGROUND: Subretinal injection (SRI) has become an important surgical method for treating vitreoretinal diseases. Nevertheless, the optimisation of bleb formation in SRI, for the attainment of desired therapeutic outcomes, still requires further in...
Applying Machine Learning to the Visual Inspection of Filled Injectable Drug Products.
PDA journal of pharmaceutical science and technology
Jun 15, 2023
With machine learning (ML), we see the potential to better harness the intelligence and decision-making abilities of human inspectors performing manual visual inspection (MVI) and apply this to automated visual inspection (AVI) with the inherent impr...
Scratch-AID, a deep learning-based system for automatic detection of mouse scratching behavior with high accuracy.
eLife
Dec 8, 2022
Mice are the most commonly used model animals for itch research and for development of anti-itch drugs. Most laboratories manually quantify mouse scratching behavior to assess itch intensity. This process is labor-intensive and limits large-scale gen...
Application of Intelligent Intravenous Drug Dispensing Robot in Clinical Nursing.
Contrast media & molecular imaging
Mar 21, 2022
In order to explore the application of intelligent intravenous drug dispensing robot in clinical nursing, the efficiency, residual amount, needle pushing, and pulling times, the incidence of accidental hand stab injury and the accuracy of drug dispen...
Modeling of the dynamics of vascular embolization by using porous media for the design of injection robots of embolic agents.
Medical engineering & physics
Feb 11, 2022
Embolization is the prevailing therapy for tumor-targeting, anti-organ hyperfunction, and hemostasis. However, the injection of embolic agents largely depends on the experiences of doctors as assisted by X-ray, which will negate the health of the doc...
Do High-Volume Injections Affect the Ultrasonographic Neovascularization in Chronic Achilles Tendinopathy? A Randomized Placebo-Controlled Clinical Trial.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Dec 9, 2021
OBJECTIVE: High-volume injections (HVIs) are thought to target neovascularization in chronic midportion Achilles tendinopathy (AT), yet the mechanism has not been clarified. Therefore, we aim to evaluate whether a HVI decreases ultrasonographic Doppl...
Effectiveness of Pre-administered Natural Sweet-tasting Solution for Decreasing Pain Associated with Dental Injections in Children: A Split-mouth Randomized Controlled Trial.
The journal of contemporary dental practice
Dec 1, 2021
AIM: This study aimed to discern if a prior intake of a natural sweet remedy (honey) impacted pain perception during intraoral injections.
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