AIMC Topic: Insulin-Secreting Cells

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Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans.

Metabolism: clinical and experimental
BACKGROUND: Loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result from circulating lipids (triacylglycerols [TG] or free fatty acids) and/or adipoc...

Long-term clinical and functional impact of biliopancreatic diversion on type 2 diabetes in morbidly and non-morbidly obese patients.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
SETTING: Obesity surgery has been proposed as a treatment option for diabetic patients with body mass index (BMI)<35 kg/m(2), but the efficacy of metabolic surgery has not been conclusively determined.

Integration of multi-omics data and machine learning to identify antioxidant biomarkers in type 1 diabetes.

Free radical biology & medicine
The identification of biomarkers for early diagnosis and monitoring the progression of Type 1 Diabetes (T1DM) is essential for improving disease management. This study integrates multi-omics data with machine learning to identify antioxidant stress p...

In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker.

Acta pharmaceutica (Zagreb, Croatia)
The corms of Hypoxis argentea are widely used as a traditional remedy for diabetes mellitus in South Africa. In this study, we investigated the effects of non-toxic concentrations (12.5-100 μg mL-1) of the aqueous extract of H. argentea (HAA) corms o...