AIMC Topic: Adipogenesis

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Bioinformatics and machine learning approaches to explore key biomarkers in muscle aging linked to adipogenesis.

BMC musculoskeletal disorders Mar 22, 2025
Adipogenesis is intricately linked to the onset and progression of muscle aging; however, the relevant biomarkers remain unclear. This study sought to identify key genes associated with adipogenesis in the context of muscle aging. Firstly, gene expre...
Humans Machine Learning Adipogenesis Aging Gene Expression Profiling Computational Biology Quadriceps Muscle Mice Animals Male Biomarkers Aged
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Cytotoxicity, Antiadipogenic, Low-Density Lipoprotein Oxidation Inhibitory Activities, and Acute Toxicity Study of Hydroethanolic Leaf and Bark Extracts.

TheScientificWorldJournal Dec 17, 2024
Obesity is increasingly taking an important stage as a cause of death worldwide, and interventions with a good cost-effectiveness ratio are needed. is one of these natural products with health benefits. Objective. The present study evaluated the cy...
Adipogenesis Lipoproteins, LDL Plant Extracts Oxidation-Reduction Male Plant Leaves Rats, Wistar Antioxidants Humans Rats Plant Bark Animals
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Identification of the lipid-lowering component of triterpenes from Alismatis rhizoma based on the MRM-based characteristic chemical profiles and support vector machine model.

Analytical and bioanalytical chemistry May 14, 2019
It has been demonstrated that triterpenes in Alismatis rhizoma (Zexie in Chinese, ZX) contributed to the lipid-lowering effect on high-fat diet-induced hyperlipidemia. Alisol B 23-acetate, one of the abundant triterpenes in ZX, was used as the marker...
Hyperlipidemias Hypolipidemic Agents Rhizome Alismataceae 3T3-L1 Cells Chromatography, High Pressure Liquid Tandem Mass Spectrometry Triterpenes Drug Evaluation, Preclinical Mice Support Vector Machine Adipogenesis Lipid Metabolism Lipids Animals Drug Discovery
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A method for evaluating the degree of Adipogenic differentiation of porcine cells cultured in suspension based on deep learning.

Food research international (Ottawa, Ont.) Jul 1, 2025
Fat plays a very important role in the quality of meat and meat products. Cell culture based adipocyte differentiation is a crucial step in the production of cell-cultured meat, traditionally relying on quantitative assessments through fluorescence s...
Animals Swine Deep Learning High-Throughput Screening Assays Cells, Cultured Adipocytes Cell Culture Techniques Adipogenesis Cell Differentiation
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Application of a deep learning-based image analysis and live-cell imaging system for quantifying adipogenic differentiation kinetics of adipose-derived stem/stromal cells.

Adipocyte Dec 1, 2021
Quantitative methods for assessing differentiative potency of adipose-derived stem/stromal cells may lead to improved clinical application of this multipotent stem cell, by advancing our understanding of specific processes such as adipogenic differen...
Adipose Tissue Adipogenesis Cells, Cultured Deep Learning Stromal Cells Cell Differentiation Kinetics
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In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker.

Acta pharmaceutica (Zagreb, Croatia) Dec 1, 2018
The corms of Hypoxis argentea are widely used as a traditional remedy for diabetes mellitus in South Africa. In this study, we investigated the effects of non-toxic concentrations (12.5-100 μg mL-1) of the aqueous extract of H. argentea (HAA) corms o...
Microscopy Adipocytes Hypoxis Insulin-Secreting Cells 3T3-L1 Cells Cell Differentiation Glucose Dose-Response Relationship, Drug Adipogenesis Animals Plant Extracts alpha-Glucosidases Swine Muscle Fibers, Skeletal alpha-Amylases Cell Proliferation Mice Hypoglycemic Agents
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