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Knee Joint

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Platelet-rich plasma inhibits Wnt/β-catenin signaling in rabbit cartilage cells activated by IL-1β.

International immunopharmacology
OBJECTIVE: Platelet-rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/β-catenin signaling in rabbit chondrocytes.

Anatomic and non-anatomic anterior cruciate ligament posterolateral bundle augmentation affects graft function.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
PURPOSE: The purpose of this study is to compare knee laxity and graft function (tissue force) between anatomic and non-anatomic posterolateral (PL) bundle augmentation.

Effect of body weight support variation on muscle activities during robot assisted gait: a dynamic simulation study.

Computer methods in biomechanics and biomedical engineering
BACKGROUND AND OBJECTIVES: While body weight support (BWS) intonation is vital during conventional gait training of neurologically challenged subjects, it is important to evaluate its effect during robot assisted gait training. In the present researc...

Design and Characterization of an Exoskeleton for Perturbing the Knee During Gait.

IEEE transactions on bio-medical engineering
OBJECTIVE: An improved understanding of mechanical impedance modulation in human joints would provide insights about the neuromechanics underlying functional movements. Experimental estimation of impedance requires specialized tools with highly repro...

Is an Anterolateral Ligament Reconstruction Required in ACL-Reconstructed Knees With Associated Injury to the Anterolateral Structures? A Robotic Analysis of Rotational Knee Stability.

The American journal of sports medicine
BACKGROUND: The effect of an anterolateral ligament (ALL) reconstruction on rotational knee stability and corresponding anterior cruciate ligament (ACL) graft forces using multiple knee loading conditions including the pivot-shift phenomenon has not ...

How Much Does the Anatomical Tibial Component Improve the Bony Coverage in Total Knee Arthroplasty?

The Journal of arthroplasty
BACKGROUND: Recently, anatomical designs in total knee arthroplasty are introduced to address asymmetry of the resected tibia cutting surface. It is still not well known how much improvement would be achieved in total knee arthroplasty, especially in...

Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.

Cartilage
Objective The objective of this study was to determine whether intra-articular injections of tenascin-C (TNC) could prevent cartilage damage in murine models of osteoarthritis (OA). Design Fluorescently labeled TNC was injected into knee joints and i...

Delaying Ambulation Mode Transition Decisions Improves Accuracy of a Flexible Control System for Powered Knee-Ankle Prosthesis.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Powered lower limb prostheses can assist users in a variety of ambulation modes by providing knee and/or ankle joint power. This study's goal was to develop a flexible control system to allow users to perform a variety of tasks in a natural, accurate...

Human-like compliant locomotion: state of the art of robotic implementations.

Bioinspiration & biomimetics
This review paper provides a synthetic yet critical overview of the key biomechanical principles of human bipedal walking and their current implementation in robotic platforms. We describe the functional role of human joints, addressing in particular...

Impact on gait biomechanics of using an active variable impedance prosthetic knee.

Journal of neuroengineering and rehabilitation
BACKGROUND: An above knee amputation can have a significant impact on gait, with substantial deviations in inter-leg symmetry, step length, hip exertion and upper body involvement even when using a current clinical standard of care prosthesis. These ...