AIMC Topic: Knowledge Bases
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ARAX: a graph-based modular reasoning tool for translational biomedicine.
Bioinformatics (Oxford, England)
Mar 1, 2023
MOTIVATION: With the rapidly growing volume of knowledge and data in biomedical databases, improved methods for knowledge-graph-based computational reasoning are needed in order to answer translational questions. Previous efforts to solve such challe...
canSAR: update to the cancer translational research and drug discovery knowledgebase.
Nucleic acids research
Jan 6, 2023
canSAR (https://cansar.ai) is the largest public cancer drug discovery and translational research knowledgebase. Now hosted in its new home at MD Anderson Cancer Center, canSAR integrates billions of experimental measurements from across molecular pr...
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2023.
Nucleic acids research
Jan 6, 2023
The National Genomics Data Center (NGDC), part of the China National Center for Bioinformation (CNCB), provides a family of database resources to support global academic and industrial communities. With the explosive accumulation of multi-omics data ...
UniProt: the Universal Protein Knowledgebase in 2023.
Nucleic acids research
Jan 6, 2023
The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this publication we describe enhancements made to our data processing...
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource.
Nucleic acids research
Jan 6, 2023
The NHGRI-EBI GWAS Catalog (www.ebi.ac.uk/gwas) is a FAIR knowledgebase providing detailed, structured, standardised and interoperable genome-wide association study (GWAS) data to >200 000 users per year from academic research, healthcare and industr...
Fungal names: a comprehensive nomenclatural repository and knowledge base for fungal taxonomy.
Nucleic acids research
Jan 6, 2023
Fungal taxonomy is a complex and rapidly changing subject, which makes proper naming of fungi challenging for taxonomists. A registration platform with a standardized and information-integrated database is a powerful tool for efficient research on fu...
AgeAnno: a knowledgebase of single-cell annotation of aging in human.
Nucleic acids research
Jan 6, 2023
Aging is a complex process that accompanied by molecular and cellular alterations. The identification of tissue-/cell type-specific biomarkers of aging and elucidation of the detailed biological mechanisms of aging-related genes at the single-cell le...
Dual-process system based on mixed semantic fusion for Chinese medical knowledge-based question answering.
Mathematical biosciences and engineering : MBE
Jan 5, 2023
Chinese medical knowledge-based question answering (cMed-KBQA) is a vital component of the intelligence question-answering assignment. Its purpose is to enable the model to comprehend questions and then deduce the proper answer from the knowledge bas...
mOWL: Python library for machine learning with biomedical ontologies.
Bioinformatics (Oxford, England)
Jan 1, 2023
MOTIVATION: Ontologies contain formal and structured information about a domain and are widely used in bioinformatics for annotation and integration of data. Several methods use ontologies to provide background knowledge in machine learning tasks, wh...
Annotation of biologically relevant ligands in UniProtKB using ChEBI.
Bioinformatics (Oxford, England)
Jan 1, 2023
MOTIVATION: To provide high quality, computationally tractable annotation of binding sites for biologically relevant (cognate) ligands in UniProtKB using the chemical ontology ChEBI (Chemical Entities of Biological Interest), to better support effort...
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