Advances in microscopy, microfluidics, and optogenetics enable single-cell monitoring and environmental regulation and offer the means to control cellular phenotypes. The development of such systems is challenging and often results in bespoke setups ...
Combining microfluidics technology with machine learning represents an innovative approach to conduct massive quantitative cell behavior study and implement smart decision-making systems in support of clinical diagnostics. The spleen plays a key-role...
The broad possibilities offered by microfluidic devices in relation to massive data monitoring and acquisition open the door to the use of deep learning technologies in a very promising field: cell culture monitoring. In this work, we develop a metho...
Sickle cell disease, a genetic disorder affecting a sizeable global demographic, manifests in sickle red blood cells (sRBCs) with altered shape and biomechanics. sRBCs show heightened adhesive interactions with inflamed endothelium, triggering painfu...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
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In this study, the potential of microfluidic systems with different microchannel geometries (microchannel with teardrop micromixers and microchannel with swirl micromixers) for the preparation of oil-in-water (O/W) emulsions using two different emuls...
A microfluidic manipulation system that can sense a liquid and control its flow is highly desirable. However, conventional sensors and motors have difficulty fitting the limited space in microfluidic devices; moreover, fast sensing and actuation are ...
A critical microchannel technique is to isolate specific objects, such as cells, in a biological solution. Generally, this particle sorting is achieved by designing a microfluidic device and tuning its control values; however, unpredictable motions o...
Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in vitro cell culture that has a promising future in the healthcare industry. The numerous advantages of OOAC over conventional systems make it highly popular. The chi...
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical to clinical translational precision. The current trends in the in vitro modeling is to reduce the complexity of human organ anatomy to the fundamental cellular...
A major challenge in the field of microfluidics is to predict and control drop interactions. This work develops an image-based data-driven model to forecast drop dynamics based on experiments performed on a microfluidics device. Reduced-order modelli...