AIMC Topic: Least-Squares Analysis

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Predictive diagnosis of major depression using NMR-based metabolomics and least-squares support vector machine.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Major depressive (MD) disorder is a serious psychiatric disorder that can result in suicidal behavior if not treated. The MD diagnosis using a standardized instrument instead of a structured interview will be advantageous for treatment an...

Tackling Missing Data in Community Health Studies Using Additive LS-SVM Classifier.

IEEE journal of biomedical and health informatics
Missing data is a common issue in community health and epidemiological studies. Direct removal of samples with missing data can lead to reduced sample size and information bias, which deteriorates the significance of the results. While data imputatio...

Simultaneous Enrichment and On-line Detection of Low-Concentration Copper, Cobalt, and Nickel Ions in Water by Near-Infrared Diffuse Reflectance Spectroscopy Combined with Chemometrics.

Journal of AOAC International
Sensitive detection of heavy metal ions in water is of great importance considering the effects that heavy metals have on public health. A developed fluidized bed enrichment technique was used to concentrate and detect low concentrations of Cu2+, Co2...

Two-Way Regularized Fuzzy Clustering of Multiple Correspondence Analysis.

Multivariate behavioral research
Multiple correspondence analysis (MCA) is a useful tool for investigating the interrelationships among dummy-coded categorical variables. MCA has been combined with clustering methods to examine whether there exist heterogeneous subclusters of a popu...

Glucose Oxidase Biosensor Modeling and Predictors Optimization by Machine Learning Methods.

Sensors (Basel, Switzerland)
Biosensors are small analytical devices incorporating a biological recognition element and a physico-chemical transducer to convert a biological signal into an electrical reading. Nowadays, their technological appeal resides in their fast performance...

PLS-LS-SVM based modeling of ATR-IR as a robust method in detection and qualification of alprazolam.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
According to the United States pharmacopeia (USP), Gold standard technique for Alprazolam determination in dosage forms is HPLC, an expensive and time-consuming method that is not easy to approach. In this study chemometrics assisted ATR-IR was intro...

Model-based reinforcement learning with dimension reduction.

Neural networks : the official journal of the International Neural Network Society
The goal of reinforcement learning is to learn an optimal policy which controls an agent to acquire the maximum cumulative reward. The model-based reinforcement learning approach learns a transition model of the environment from data, and then derive...

Predicting and communicating flood risk of transport infrastructure based on watershed characteristics.

Journal of environmental management
This research aims to identify and communicate water-related vulnerabilities in transport infrastructure, specifically flood risk of road/rail-stream intersections, based on watershed characteristics. This was done using flooding in Värmland and Väst...

Batch Mode TD($\lambda$ ) for Controlling Partially Observable Gene Regulatory Networks.

IEEE/ACM transactions on computational biology and bioinformatics
External control of gene regulatory networks (GRNs) has received much attention in recent years. The aim is to find a series of actions to apply to a gene regulation system making it avoid its diseased states. In this work, we propose a novel method ...

Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images.

Computational and mathematical methods in medicine
The focus of this research is on automated identification of the quality of human induced pluripotent stem cell (iPSC) colony images. iPS cell technology is a contemporary method by which the patient's cells are reprogrammed back to stem cells and ar...