Cardiovascular disease progression is characterised by the dysregulation of lipid metabolism and pro-atherogenic effects of adipose tissue signalling. Recent findings from the analysis of transcriptomic data in bulk tissue has enabled these insights ...
Internalizing problems (e.g., anxiety and depression) are associated with a wide range of adverse outcomes. While some predictors of internalizing problems are known (e.g., their frequent co-occurrence with neurodevelopmental (ND) conditions), the bi...
BACKGROUND: Suicide represents a significant challenge to public health that calls for a suitable intervention from the healthcare sector. Despite the typically low suicide rate among most Muslim nations, research indicates that there is an increase ...
BACKGROUND: Arthritis is a prevalent chronic disease substantially impacting patients' quality of life (QoL). While identifying key determinants associated with arthritis is critical for targeted interventions, traditional statistical methods often s...
OBJECTIVE: To explore the mechanisms of acupuncture-induced neck pain relief and identify appropriate candidates using neuroimaging and machine learning techniques.
BACKGROUND: Depression is highly recurrent and heterogeneous. The unobtrusive, continuous collection of mobile sensing data via smartphones and wearable devices offers a promising approach to monitor and predict individual depression trajectories, di...
BACKGROUND: Knee osteoarthritis (KOA) worsens both structurally and symptomatically, yet no model predicts KOA progression using Magnetic Resonance Image (MRI) radiomics and biomarkers. This study aimed to develop and test the longitudinal Load-Beari...
Falls are a critical concern in older adults with cognitive frailty (CF). However, previous studies have not fully examined whether machine learning models can predict falls in older individuals with CF. The 2-year longitudinal data set from the Kore...
Neurology(R) neuroimmunology & neuroinflammation
Aug 19, 2025
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)...
Longitudinal serological proteomic dynamics during antiviral therapy (AVT) in chronic hepatitis B (CHB) patients with liver fibrosis remain poorly characterized. Here, using four-dimensional data-independent acquisition mass spectrometry (4D-DIA-MS),...
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