Computer methods and programs in biomedicine
Sep 1, 2025
BACKGROUND AND OBJECTIVE: In lung radiotherapy, infrared cameras can track reflective objects on the chest to estimate tumor motion due to breathing. However, treatment system latencies hinder radiation beam precision. Real-time recurrent learning (R...
OBJECTIVE: This study aims to develop and validate a PET/CT radiomics fusion model for preoperative predicting pleural invasion (PI) in non-small cell lung cancer (NSCLC) patients.
RATIONALE AND OBJECTIVES: The aim of this study is to develop a deep learning-based multimodal feature interaction-guided fusion (DL-MFIF) framework that integrates macroscopic information from computed tomography (CT) images with microscopic informa...
RATIONALE AND OBJECTIVES: Radiogenomics holds promise in identifying molecular alterations in nonsmall cell lung cancer (NSCLC) using imaging features. Previously, we developed a radiogenomics model to predict epidermal growth factor receptor (EGFR) ...
Annals of the American Thoracic Society
Sep 1, 2025
Incidental features of interstitial lung disease (ILD) are commonly observed on chest computed tomography (CT) scans and are independently associated with poor outcomes. Although most studies to date have relied on qualitative assessments of ILD, qu...
Currently, chemotherapy drugs are the first-line treatment for lung cancer patients, and evaluating their efficacy is of utmost significance. However, assessing the clinical efficacy of chemotherapy drugs remains a challenging task. In recent years, ...
Studies in health technology and informatics
Aug 7, 2025
Lung cancer is one of the most common and lethal types of cancer. Early diagnosis and appropriate treatment play a crucial role in reducing mortality. Artificial intelligence techniques can be used to support clinical approaches to lung cancer, helpi...
BACKGROUND: With the widespread adoption of low-dose CT screening, the detection of pulmonary ground-glass nodules (GGNs) has risen markedly, presenting diagnostic challenges in distinguishing preinvasive lesions from invasive adenocarcinomas (IAC). ...
Journal of cellular and molecular medicine
Aug 1, 2025
The immunoregulatory functions and clinical implications of APOE+ macrophages within the tumour microenvironment of lung adenocarcinoma remain incompletely defined. In this study, single-cell transcriptome analysis revealed distinct subsets of APOE+ ...
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