AIMC Topic: Machine Learning

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Developing the Total Health Profile, a Generalizable Unified Set of Multimorbidity Risk Scores Derived From Machine Learning for Broad Patient Populations: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Multimorbidity clinical risk scores allow clinicians to quickly assess their patients' health for decision making, often for recommendation to care management programs. However, these scores are limited by several issues: existing multimo...

Using explainable machine learning to characterise data drift and detect emergent health risks for emergency department admissions during COVID-19.

Scientific reports
A key task of emergency departments is to promptly identify patients who require hospital admission. Early identification ensures patient safety and aids organisational planning. Supervised machine learning algorithms can use data describing historic...

Combining machine learning and conventional statistical approaches for risk factor discovery in a large cohort study.

Scientific reports
We present a simple and efficient hypothesis-free machine learning pipeline for risk factor discovery that accounts for non-linearity and interaction in large biomedical databases with minimal variable pre-processing. In this study, mortality models ...

Reduced and stable feature sets selection with random forest for neurons segmentation in histological images of macaque brain.

Scientific reports
In preclinical research, histology images are produced using powerful optical microscopes to digitize entire sections at cell scale. Quantification of stained tissue relies on machine learning driven segmentation. However, such methods require multip...

Enhancing preclinical drug discovery with artificial intelligence.

Drug discovery today
Artificial intelligence (AI) is becoming an integral part of drug discovery. It has the potential to deliver across the drug discovery and development value chain, starting from target identification and reaching through clinical development. In this...

A deep learning approach in automated detection of schizophrenia using scalogram images of EEG signals.

Physical and engineering sciences in medicine
This study presents a method with high accuracy performance that aims to automatically detect schizophrenia (SZ) from electroencephalography (EEG) records. Unlike related literature studies using traditional machine learning algorithms, the features ...

Feedforward neural networks initialization based on discriminant learning.

Neural networks : the official journal of the International Neural Network Society
In this paper, a novel data-driven method for weight initialization of Multilayer Perceptrons and Convolutional Neural Networks based on discriminant learning is proposed. The approach relaxes some of the limitations of competing data-driven methods,...

Sparsely Connected Autoencoders: A Multi-Purpose Tool for Single Cell omics Analysis.

International journal of molecular sciences
BACKGROUND: Biological processes are based on complex networks of cells and molecules. Single cell multi-omics is a new tool aiming to provide new incites in the complex network of events controlling the functionality of the cell.