While machine learning (ML) approaches are commonly utilized in medical diagnostics, the accuracy of these methods in identifying psoriatic arthritis (PsA) remains uncertain. To evaluate the accuracy of ML approaches in the medical diagnosis of PsA. ...
BACKGROUND: Cacao (Theobroma cacao L.) breeding and improvement rely on understanding germplasm diversity and trait architecture. This study characterized a cacao collection (173 accessions) evaluated in Puerto Rico, examining phenotypic diversity, t...
Adherence to antiretroviral therapy (ART) is critical for HIV treatment success, yet the impact of tuberculosis preventive therapy (TPT) remains inadequately understood. Using observational data from 4152 HIV patients in Ethiopia (2005-2024), we appl...
BACKGROUND: Abnormal hedgehog (Hh) signaling is linked to preeclampsia (PE). This study aimed to identify Hh-related diagnostic biomarkers for PE and assess the role of immune infiltration.
BACKGROUND: Bioactive natural products represent a vital resource for combating human diseases. However, their discovery often encounters multiple challenges. Bioactivity-guided isolation can yield bioactive compounds but are labor-intensive and have...
Coastal wetlands of the Indus River Delta are vital ecological regions that have undergone significant transformations driven by anthropogenic activities and environmental stressors. This study assesses the dynamics of wetlands and reclamation in the...
Journal of chemical information and modeling
Aug 8, 2025
This study used machine learning models to investigate the potential of biosorbents derived from natural fruit seed waste (apricot, almond, and walnut) for removing a cationic dye. Levulinic acid (LA)-modified powders of almond shell (ASh), apricot k...
BACKGROUND: Sepsis is frequently combined with acute liver failure (ALF), a critical determinant in the mortality of septic patients. Pyroptosis is a significant form of programmed cell death that plays an important role in the inflammatory response....
BMC medical informatics and decision making
Aug 8, 2025
BACKGROUND: Anti-programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy has revolutionized cancer treatment. However, it can cause immune-related adverse events, including acute kidney injury (AKI). Such adverse e...
COVID-19 has posed a significant global health challenge, affecting individuals across all age groups. While extensive research has focused on adults, pediatric patients exhibit distinct clinical characteristics that necessitate specialized predictiv...
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