AIMC Topic: Machine Learning

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DCMD: Distance-based classification using mixture distributions on microbiome data.

PLoS computational biology
Current advances in next-generation sequencing techniques have allowed researchers to conduct comprehensive research on the microbiome and human diseases, with recent studies identifying associations between the human microbiome and health outcomes f...

Machine Learning Generated Synthetic Faces for Use in Facial Aesthetic Research.

Facial plastic surgery & aesthetic medicine
A centralized repository of clinically applicable facial images with unrestricted use would facilitate facial aesthetic research. Using a machine learning neural network, we aim to (1) create a repository of synthetic faces that can be used for fac...

Detection of prenatal alcohol exposure using machine learning classification of resting-state functional network connectivity data.

Alcohol (Fayetteville, N.Y.)
Fetal Alcohol Spectrum Disorder (FASD), a wide range of physical and neurobehavioral abnormalities associated with prenatal alcohol exposure (PAE), is recognized as a significant public health concern. Advancements in the diagnosis of FASD have been ...

Refinement of the clinical variant interpretation framework by statistical evidence and machine learning.

Med (New York, N.Y.)
BACKGROUND: Although the American College of Medical Genetics andĀ Genomics/Association for Molecular Pathology (ACMG/AMP) guidelines for variant interpretation are used widely in clinical genetics, there is room for improvement of these knowledge-bas...

A two-stage modeling approach for breast cancer survivability prediction.

International journal of medical informatics
BACKGROUND: Despite the increasing number of studies in breast cancer survival prediction, there is little attention put toward deceased patients and their survival lengths. Moreover, developing a model that is both accurate and interpretable remains...

Multi-source Seq2seq guided by knowledge for Chinese healthcare consultation.

Journal of biomedical informatics
Online healthcare consultation offers people a convenient way to consult doctors. In this paper, we aim at building a generative dialog system for Chinese healthcare consultation. As the original Seq2seq architecture tends to suffer the issue of gene...

Precision medicine and machine learning towards the prediction of the outcome of potential celiac disease.

Scientific reports
Potential Celiac Patients (PCD) bear the Celiac Disease (CD) genetic predisposition, a significant production of antihuman transglutaminase antibodies, but no morphological changes in the small bowel mucosa. A minority of patients (17%) showed clinic...

Prediction of tau accumulation in prodromal Alzheimer's disease using an ensemble machine learning approach.

Scientific reports
We developed machine learning (ML) algorithms to predict abnormal tau accumulation among patients with prodromal AD. We recruited 64 patients with prodromal AD using the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. Supervised ML approa...

Diagnosis prediction of tumours of unknown origin using ImmunoGenius, a machine learning-based expert system for immunohistochemistry profile interpretation.

Diagnostic pathology
BACKGROUND: Immunohistochemistry (IHC) remains the gold standard for the diagnosis of pathological diseases. This technique has been supporting pathologists in making precise decisions regarding differential diagnosis and subtyping, and in creating p...