AIMC Topic: Machine Learning

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LogDet Rank Minimization with Application to Subspace Clustering.

Computational intelligence and neuroscience
Low-rank matrix is desired in many machine learning and computer vision problems. Most of the recent studies use the nuclear norm as a convex surrogate of the rank operator. However, all singular values are simply added together by the nuclear norm, ...

On the creation of a clinical gold standard corpus in Spanish: Mining adverse drug reactions.

Journal of biomedical informatics
The advances achieved in Natural Language Processing make it possible to automatically mine information from electronically created documents. Many Natural Language Processing methods that extract information from texts make use of annotated corpora,...

Benefit of Retraining pKa Models Studied Using Internally Measured Data.

Journal of chemical information and modeling
The ionization state of drugs influences many pharmaceutical properties such as their solubility, permeability, and biological activity. It is therefore important to understand the structure property relationship for the acid-base dissociation consta...

A Generalizable Brain-Computer Interface (BCI) Using Machine Learning for Feature Discovery.

PloS one
This work describes a generalized method for classifying motor-related neural signals for a brain-computer interface (BCI), based on a stochastic machine learning method. The method differs from the various feature extraction and selection techniques...

Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.

PLoS neglected tropical diseases
BACKGROUND: Chagas disease is a neglected tropical disease (NTD) caused by the eukaryotic parasite Trypanosoma cruzi. The current clinical and preclinical pipeline for T. cruzi is extremely sparse and lacks drug target diversity.

RobotReviewer: evaluation of a system for automatically assessing bias in clinical trials.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To develop and evaluate RobotReviewer, a machine learning (ML) system that automatically assesses bias in clinical trials. From a (PDF-formatted) trial report, the system should determine risks of bias for the domains defined by the Cochra...

Realization problem of multi-layer cellular neural networks.

Neural networks : the official journal of the International Neural Network Society
This paper investigates whether the output space of a multi-layer cellular neural network can be realized via a single layer cellular neural network in the sense of the existence of finite-to-one map from one output space to the other. Whenever such ...

Improving prediction of secondary structure, local backbone angles, and solvent accessible surface area of proteins by iterative deep learning.

Scientific reports
Direct prediction of protein structure from sequence is a challenging problem. An effective approach is to break it up into independent sub-problems. These sub-problems such as prediction of protein secondary structure can then be solved independentl...

A Sensitive and Specific Neural Signature for Picture-Induced Negative Affect.

PLoS biology
Neuroimaging has identified many correlates of emotion but has not yet yielded brain representations predictive of the intensity of emotional experiences in individuals. We used machine learning to identify a sensitive and specific signature of emoti...