Multiplex tissue imaging enables single-cell spatial proteomics and transcriptomics but remains limited by incomplete molecular profiling, tissue loss, and probe failure. Here, we apply machine learning to impute single-cell protein abundance using m...
The British journal of general practice : the journal of the Royal College of General Practitioners
May 22, 2025
BACKGROUND: Digital technologies are transforming healthcare delivery by enhancing accessibility and providing innovative ways to manage increasing patient demand. With the rise of artificial intelligence (AI) and machine learning (ML), a tsunami of ...
Machine learning applications in protein sciences have ushered in a new era for designing molecules in silico. Antibodies, which currently form the largest group of biologics in clinical use, stand to benefit greatly from this shift. Despite the prol...
Feature selection is a crucial preprocessing step in the fields of machine learning, data mining and pattern recognition. In medical data analysis, the large number and complexity of features are often accompanied by redundant or irrelevant features,...
AMIA ... Annual Symposium proceedings. AMIA Symposium
May 22, 2025
Communicating Narrative Concerns Entered by RNs Early Warning System (CONCERN EWS) is a machine-learning predictive model that leverages nursing surveillance documentation patterns to predict deterioration risks for hospitalized patients. In a retros...
Identifying cell-type-specific enhancers is critical for developing genetic tools to study the mammalian brain. We organized the "Brain Initiative Cell Census Network (BICCN) Challenge: Predicting Functional Cell Type-Specific Enhancers from Cross-Sp...
Neoantigens have emerged as ideal targets for personalized cancer immunotherapy. We depict the pan-cancer peptide atlas by comprehensively collecting immunopeptidomics from 531 samples across 14 cancer and 29 normal tissues, and identify 389,165 cano...
Pathogenic yeasts are an increasing concern in healthcare, with species like often displaying drug resistance and causing high mortality in immunocompromised patients. The need for rapid and accessible diagnostic methods for accurate yeast identific...
Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience. The use of artificial intelligence to identify morphological patterns in erythrocytes would imp...
OBJECTIVE: This study aimed to develop a predictive model for secondary infections in patients with severe or critical COVID-19 by analyzing clinical characteristics and laboratory indicators.
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