Ecotoxicology and environmental safety
Apr 6, 2025
Soil contamination by potentially toxic elements (PTEs) poses substantial risks to the environment and human health. Traditional investigational methods are often inadequate for large-scale assessments because they are time-consuming, costly, and hav...
Muscle-Invasive Bladder Cancer (MIBC) is a more aggressive disease than non-muscle-invasive bladder cancer (NMIBC), with greater chances of metastasis. We sought to develop machine learning (ML) models to predict metastasis and prognosis in MIBC pati...
Progress in the development of molecular-targeted therapies in the field of inflammatory bowel disease has been remarkable. With the advent of molecular-targeted agents, treatment strategies have changed, and higher-level treatment goals have been se...
The precise identification of tumor T-cell antigens (TTCAs) is crucial for advancements in cancer immunotherapy and other clinical uses. In contrast to the labor-intensive and time-consuming process of experimentally identifying TTCAs, computational ...
Neural networks : the official journal of the International Neural Network Society
Apr 5, 2025
Continual learning (CL) has received a surge of interest, particularly in parameter isolation approaches, aiming to prevent catastrophic forgetting by assigning a disjoint parameter set to each task. Despite their effectiveness, existing approaches o...
Agarase enzymes are critical in industries like food, cosmetics, and medicine where they play a critical role in DNA recovery, food gelling, cosmetic formulations, and waste treatment. However, current agarase sources often face limitations related t...
Quantifying organic properties is pivotal for enhancing the precision and interpretability of degradation predictive machine learning (ML) models. This study used Binary Morgan Fingerprints (B-MF) and Count-Based Morgan Fingerprints (C-MF) to quantif...
Journal of chemical theory and computation
Apr 5, 2025
Directionality in molecular and biomolecular networks plays an important role in the accurate representation of the complex, dynamic, and asymmetrical nature of interactions present in protein-ligand binding, signal transduction, and biological pathw...
BACKGROUND: Neutrophils play a key role in the tumor microenvironment (TME); however, their functions in glioblastoma (GBM) are overlooked and insufficiently studied. A detailed analysis of GBM-associated neutrophil (GBMAN) subpopulations may offer n...
The burden of diabetic foot ulcers (DFU) is exacerbated in diabetic patients with concomitant arteriosclerotic occlusion disease (ASO) in the lower extremities, who experience more severe symptoms and poorer prognoses. The study aims to develop a pre...
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