AIMC Topic: Microscopy, Confocal

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Deep Learning for Basal Cell Carcinoma Detection for Reflectance Confocal Microscopy.

The Journal of investigative dermatology
Basal cell carcinoma (BCC) is the most common skin cancer, with over 2 million cases diagnosed annually in the United States. Conventionally, BCC is diagnosed by naked eye examination and dermoscopy. Suspicious lesions are either removed or biopsied ...

A deep transfer learning framework for the automated assessment of corneal inflammation on in vivo confocal microscopy images.

PloS one
PURPOSE: Infiltration of activated dendritic cells and inflammatory cells in cornea represents an important marker for defining corneal inflammation. Deep transfer learning has presented a promising potential and is gaining more importance in compute...

An open-source semi-automated robotics pipeline for embryo immunohistochemistry.

Scientific reports
A significant challenge for developmental systems biology is balancing throughput with controlled conditions that minimize experimental artifacts. Large-scale developmental screens such as unbiased mutagenesis surveys have been limited in their appli...

Red blood cell phenotyping from 3D confocal images using artificial neural networks.

PLoS computational biology
The investigation of cell shapes mostly relies on the manual classification of 2D images, causing a subjective and time consuming evaluation based on a portion of the cell surface. We present a dual-stage neural network architecture for analyzing fin...

Digital Frozen Sections with Fluorescence Confocal Microscopy During Robot-assisted Radical Prostatectomy: Surgical Technique.

European urology
BACKGROUND: Robot-assisted radical prostatectomy (RARP) involves a tradeoff between oncological control and functional outcomes. Intraoperative control of surgical margins (SMs) may help in ensuring the safety of the dissection. Fluorescence confocal...

Improving axial resolution in Structured Illumination Microscopy using deep learning.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Structured Illumination Microscopy (SIM) is a widespread methodology to image live and fixed biological structures smaller than the diffraction limits of conventional optical microscopy. Using recent advances in image up-scaling through deep learning...

Deep Learning-Based Denoising in High-Speed Portable Reflectance Confocal Microscopy.

Lasers in surgery and medicine
BACKGROUND AND OBJECTIVE: Portable confocal microscopy (PCM) is a low-cost reflectance confocal microscopy technique that can visualize cellular details of human skin in vivo. When PCM images are acquired with a short exposure time to reduce motion b...

Deep Learning Algorithm for the Confirmation of Mucosal Healing in Crohn's Disease, Based on Confocal Laser Endomicroscopy Images.

Journal of gastrointestinal and liver diseases : JGLD
BACKGROUND AND AIMS: Mucosal healing (MH) is associated with a stable course of Crohn's disease (CD) which can be assessed by confocal laser endomicroscopy (CLE). To minimize the operator's errors and automate assessment of CLE images, we used a deep...