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Microscopy

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GRUU-Net: Integrated convolutional and gated recurrent neural network for cell segmentation.

Medical image analysis
Cell segmentation in microscopy images is a common and challenging task. In recent years, deep neural networks achieved remarkable improvements in the field of computer vision. The dominant paradigm in segmentation is using convolutional neural netwo...

A low-cost, automated parasite diagnostic system via a portable, robotic microscope and deep learning.

Journal of biophotonics
Manual hand counting of parasites in fecal samples requires costly components and substantial expertise, limiting its use in resource-constrained settings and encouraging overuse of prophylactic medication. To address this issue, a cost-effective, au...

Pathologist-level classification of histopathological melanoma images with deep neural networks.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: The diagnosis of most cancers is made by a board-certified pathologist based on a tissue biopsy under the microscope. Recent research reveals a high discordance between individual pathologists. For melanoma, the literature reports 25-26% ...

Breast cancer outcome prediction with tumour tissue images and machine learning.

Breast cancer research and treatment
PURPOSE: Recent advances in machine learning have enabled better understanding of large and complex visual data. Here, we aim to investigate patient outcome prediction with a machine learning method using only an image of tumour sample as an input.

The role of AI classifiers in skin cancer images.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
BACKGROUND: The use of different imaging modalities to assist in skin cancer diagnosis is a common practice in clinical scenarios. Different features representative of the lesion under evaluation can be retrieved from image analysis and processing. H...

Cancer taxonomy: pathology beyond pathology.

European journal of cancer (Oxford, England : 1990)
The way we categorise and classify cancer types dictates not only the way we diagnose and treat patients but also many of our decisions on biomarker and drug development. In addition, cancer taxonomy proves the ground truth for future discoveries in ...

Biomedical Image Processing with Containers and Deep Learning: An Automated Analysis Pipeline: Data architecture, artificial intelligence, automated processing, containerization, and clusters orchestration ease the transition from data acquisition to insights in medium-to-large datasets.

BioEssays : news and reviews in molecular, cellular and developmental biology
Here, a streamlined, scalable, laboratory approach is discussed that enables medium-to-large dataset analysis. The presented approach combines data management, artificial intelligence, containerization, cluster orchestration, and quality control in a...

Automatic segmentation of Sperm's parts in microscopic images of human semen smears using concatenated learning approaches.

Computers in biology and medicine
Accurate segmentation of the sperms in microscopic semen smear images is a prerequisite step in automatic sperm morphology analysis. It is a challenging task due to the non-uniform distribution of light in semen smear images, low contrast between spe...

Machine Learning with Optical Phase Signatures for Phenotypic Profiling of Cell Lines.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Robust and reproducible profiling of cell lines is essential for phenotypic screening assays. The goals of this study were to determine robust and reproducible optical phase signatures of cell lines for classification with machine learning and to cor...

Fast and reliable determination of Escherichia coli susceptibility to antibiotics: Infrared microscopy in tandem with machine learning algorithms.

Journal of biophotonics
Antimicrobial drugs have an important role in controlling bacterial infectious diseases. However, the increasing resistance of bacteria to antibiotics has become a global health care problem. Rapid determination of antimicrobial susceptibility of cli...