Portal hypertension (PHT) is pivotal in managing decompensated cirrhosis. In clinical practice, hepatic venous collaterals are frequently present, often leading to failure or reduced accuracy of hepatic venous pressure gradient (HVPG) measurements, t...
Patient satisfaction is a crucial measure of healthcare quality, influencing both health outcomes and care experiences. This study aims to identify the factors influencing patient satisfaction in healthcare facilities using machine learning algorithm...
Non-invasive preoperative assessment of HER2 status is critical for identifying candidates for targeted therapy and personalizing treatment strategies in endometrial cancer (EC). This study aims to assess the preoperative value of multiparametric mag...
Signal transduction and targeted therapy
Oct 13, 2025
Nearly 30% of patients with schizophrenia respond inadequately to current antipsychotics, with unclear markers and mechanisms of antipsychotic efficacy. A total of 208 patients with schizophrenia treated for 6 weeks with oral paliperidone were analyz...
BACKGROUND: Chronic obstructive pulmonary disease (COPD) remains a leading global health burden. In primary care, the inconsistent availability of spirometry and symptom scores limits the detection of patients with poor disease control. There is a pr...
PURPOSE: Obstructive sleep apnea (OSA) is highly prevalent among obese individuals, with a complex and bidirectional relationship wherein obesity not only serves as a primary risk factor for OSA but also exacerbates its severity. This interconnection...
This study aims to enhance individual hypertension risk prediction in Indonesia using machine learning (ML) models. The research investigates the predictive accuracy of models with and without incorporating personal hypertension history, seeking to u...
BACKGROUND: Herpes zoster (HZ) poses a growing public health challenge among adults aged 50 and above, with vaccine hesitancy being a major barrier to improving immunization rates. Understanding the factors driving HZ vaccine hesitancy is essential f...
BACKGROUND: Depressive symptoms and multiple chronic diseases (MCDs) significantly contribute to the global disease burden among middle-aged and older adults, while few studies have considered the long-term dynamics of depressive symptoms or employed...
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