Single amino acid variation (SAV) is an amino acid substitution of the protein sequence that can potentially influence the entire protein structure or function, as well as its binding affinity. Protein destabilization is related to diseases, includin...
BACKGROUND: Early detection of postoperative complications, including organ failure, is pivotal in the initiation of targeted treatment strategies aimed at attenuating organ damage. In an era of increasing health-care costs and limited financial reso...
The age of precision medicine demands powerful computational techniques to handle high-dimensional patient data. We present MultiSurv, a multimodal deep learning method for long-term pan-cancer survival prediction. MultiSurv uses dedicated submodels ...
BACKGROUND: Among patients with acute respiratory failure requiring prolonged mechanical ventilation, tracheostomies are typically placed after approximately 7 to 10 days. Yet half of patients admitted to the intensive care unit receiving tracheostom...
Effective soil spectral band selection and modeling methods can improve modeling accuracy. To establish a hyperspectral prediction model of soil organic matter (SOM) content, this study investigated a forested Eucalyptus plantation in Huangmian Fores...
Entropy is an important index for describing the structure, function, and evolution of network. The existing research on entropy is primarily applied to undirected networks. Compared with an undirected network, a directed network involves a special a...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 3, 2021
Visualization of biological mechanisms by means of pathway graphs is necessary to better understand the often complex underlying system. Manual layout of such pathways or maps of knowledge is a difficult and time consuming process. Node duplication i...
Brucellosis is one of the major public health problems in China, and human brucellosis represents a serious public health concern in Xinjiang and requires a prediction analysis to help making early planning and putting forward science preventive and ...
International journal of medical sciences
Jun 1, 2021
Chronic airway diseases are characterized by airway inflammation, obstruction, and remodeling and show high prevalence, especially in developing countries. Among them, asthma and chronic obstructive pulmonary disease (COPD) show the highest morbidity...
In the field of machine learning, building models and measuring their performance are two equally important tasks. Currently, measures of precision of regression models' predictions are usually based on the notion of mean error, where by error we mea...