AIMC Topic: Models, Neurological

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Optimizing Machine Learning Methods to Improve Predictive Models of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD
BACKGROUND: Predicting clinical course of cognitive decline can boost clinical trials' power and improve our clinical decision-making. Machine learning (ML) algorithms are specifically designed for the purpose of prediction; however. identifying opti...

Neural Encoding and Decoding with Deep Learning for Dynamic Natural Vision.

Cerebral cortex (New York, N.Y. : 1991)
Convolutional neural network (CNN) driven by image recognition has been shown to be able to explain cortical responses to static pictures at ventral-stream areas. Here, we further showed that such CNN could reliably predict and decode functional magn...

Propagation delays determine neuronal activity and synaptic connectivity patterns emerging in plastic neuronal networks.

Chaos (Woodbury, N.Y.)
In plastic neuronal networks, the synaptic strengths are adapted to the neuronal activity. Specifically, spike-timing-dependent plasticity (STDP) is a fundamental mechanism that modifies the synaptic strengths based on the relative timing of pre- and...

Global firing rate contrast enhancement in E/I neuronal networks by recurrent synchronized inhibition.

Chaos (Woodbury, N.Y.)
Inhibitory synchronization is commonly observed and may play some important functional roles in excitatory/inhibitory (E/I) neuronal networks. The firing rate contrast enhancement is a general feature of information processing in sensory pathways, an...

Chaos versus noise as drivers of multistability in neural networks.

Chaos (Woodbury, N.Y.)
The multistable behavior of neural networks is actively being studied as a landmark of ongoing cerebral activity, reported in both functional Magnetic Resonance Imaging (fMRI) and electro- or magnetoencephalography recordings. This consists of a cont...

A Dynamical Systems Perspective on Flexible Motor Timing.

Trends in cognitive sciences
A hallmark of higher brain function is the ability to rapidly and flexibly adjust behavioral responses based on internal and external cues. Here, we examine the computational principles that allow decisions and actions to unfold flexibly in time. We ...

Multivariate machine learning distinguishes cross-network dynamic functional connectivity patterns in state and trait neuropathic pain.

Pain
Communication within the brain is dynamic. Chronic pain can also be dynamic, with varying intensities experienced over time. Little is known of how brain dynamics are disrupted in chronic pain, or relates to patients' pain assessed at various timesca...

Spiking Neural Networks with Unsupervised Learning Based on STDP Using Resistive Synaptic Devices and Analog CMOS Neuron Circuit.

Journal of nanoscience and nanotechnology
We designed the CMOS analog integrate and fire (I&F) neuron circuit can drive resistive synaptic device. The neuron circuit consists of a current mirror for spatial integration, a capacitor for temporal integration, asymmetric negative and positive p...