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Multiple Sclerosis, Chronic Progressive

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The effects of robot-assisted gait training in progressive multiple sclerosis: A randomized controlled trial.

Multiple sclerosis (Houndmills, Basingstoke, England)
BACKGROUND: Gait and mobility impairments are common in progressive multiple sclerosis (MS), leading to reduced quality of life (QoL).

Progressive Multiple Sclerosis Transcriptome Deconvolution Indicates Increased M2 Macrophages in Inactive Lesions.

European neurology
Accumulating evidence suggests M2 macrophages contribute to tissue reparation and limit inflammation in multiple sclerosis (MS). However, most studies have focused on murine models without substantial support through human MS observations. The presen...

Estimating individual treatment effect on disability progression in multiple sclerosis using deep learning.

Nature communications
Disability progression in multiple sclerosis remains resistant to treatment. The absence of a suitable biomarker to allow for phase 2 clinical trials presents a high barrier for drug development. We propose to enable short proof-of-concept trials by ...