AIMC Topic: Myeloid Differentiation Factor 88

Clear Filters Showing 1 to 4 of 4 articles

Mechanistic role of pyroptosis in Kawasaki disease: An integrative bioinformatics analysis of immune dysregulation, machine learning-based biomarker discovery, WGCNA, and drug repurposing insights.

PloS one Jan 1, 2025
Kawasaki disease (KD) is an acute vasculitis that primarily affects children under five and is a leading cause of acquired heart disease in this age group. Despite the standard treatment with intravenous immunoglobulin (IVIG), approximately 10-20% of...
Gene Regulatory Networks Computational Biology Gene Expression Profiling Transcriptome Pyroptosis Myeloid Differentiation Factor 88 Mucocutaneous Lymph Node Syndrome Drug Repositioning Humans Machine Learning Biomarkers Molecular Docking Simulation
View on PubMed DOI

Machine learning-based identification of a cell death-related signature associated with prognosis and immune infiltration in glioma.

Journal of cellular and molecular medicine Jun 1, 2024
Accumulating evidence suggests that a wide variety of cell deaths are deeply involved in cancer immunity. However, their roles in glioma have not been explored. We employed a logistic regression model with the shrinkage regularization operator (LASSO...
Gene Expression Profiling Transcriptome Middle Aged Nomograms Glioma ROC Curve Gene Expression Regulation, Neoplastic Female Biomarkers, Tumor Brain Neoplasms Male Machine Learning Prognosis Humans Lymphocytes, Tumor-Infiltrating Cell Death Myeloid Differentiation Factor 88
View on PubMed DOI

[Effects of ATP on expression of inflammatory factors in endothelial progenitor cells induced by LPS and the mechanisms].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Dec 28, 2018
To investigate the effects of adenosine triphosphate (ATP) on expression of inflammatory factors induced by lipopolysaccharide (LPS) in endothelial progenitor cells (EPCs), and to elucidate the possible mechanisms.
 Methods: Mononuclear cells were is...
Lipopolysaccharide Receptors Signal Transduction Gene Expression Regulation Toll-Like Receptor 4 Myeloid Differentiation Factor 88 Lipopolysaccharides NF-kappa B Humans Leukocytes, Mononuclear Adenosine Triphosphate Endothelial Progenitor Cells
View on PubMed DOI

Metformin Alleviates Lipopolysaccharide-induced Acute Lung Injury through Suppressing Toll-like Receptor 4 Signaling.

Iranian journal of allergy, asthma, and immunology Dec 1, 2016
Signaling AMP-activated protein kinase (AMPK), an energy sensing enzyme, has been implicated in controlling inflammation. In this study we investigated whether activation of AMPK by metformin could protect the lung from lipopolysaccharide (LPS)-induc...
Animals Rats, Wistar Tumor Necrosis Factor-alpha Male Myeloid Differentiation Factor 88 Rats Hypoglycemic Agents Lung Real-Time Polymerase Chain Reaction Toll-Like Receptor 4 RNA, Messenger Peroxidase Lipopolysaccharides Blotting, Western AMP-Activated Protein Kinases Acute Lung Injury NF-kappa B Metformin
View on PubMed
Popular Topics
Recent Journals