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Neoplasm Recurrence, Local

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Local recurrence of robot-assisted total mesorectal excision: a multicentre cohort study evaluating the initial cases.

International journal of colorectal disease
PURPOSE: Evidence regarding local recurrence rates in the initial cases after implementation of robot-assisted total mesorectal excision is limited. This study aims to describe local recurrence rates in four large Dutch centres during their initial c...

Deep learning with whole slide images can improve the prognostic risk stratification with stage III colorectal cancer.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Adjuvant chemotherapy is recommended as standard treatment for colorectal cancer (CRC) with stage III according to TNM stage. However, outcomes are varied even among patients receiving similar treatments. We aimed to develop...

Deep learning signatures reveal multiscale intratumor heterogeneity associated with biological functions and survival in recurrent nasopharyngeal carcinoma.

European journal of nuclear medicine and molecular imaging
PURPOSE: How to discriminate different risks of recurrent nasopharyngeal carcinoma (rNPC) patients and guide individual treatment has become of great importance. This study aimed to explore the associations between deep learning signatures and biolog...

Deep learning approach of diffusion-weighted imaging as an outcome predictor in laryngeal and hypopharyngeal cancer patients with radiotherapy-related curative treatment: a preliminary study.

European radiology
OBJECTIVES: This preliminary study aimed to develop a deep learning (DL) model using diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps to predict local recurrence and 2-year progression-free survival (PFS) in laryngeal an...

Prediction of lymph node metastasis in early colorectal cancer based on histologic images by artificial intelligence.

Scientific reports
Risk evaluation of lymph node metastasis (LNM) for endoscopically resected submucosal invasive (T1) colorectal cancers (CRC) is critical for determining therapeutic strategies, but interobserver variability for histologic evaluation remains a major p...

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer.

Nature communications
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs remains largely unexplored. In this study, we develope a machine learning-base...