AIMC Topic: Neural Inhibition

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Neural network model of an amphibian ventilatory central pattern generator.

Journal of computational neuroscience
The neuronal multiunit model presented here is a formal model of the central pattern generator (CPG) of the amphibian ventilatory neural network, inspired by experimental data from Pelophylax ridibundus. The kernel of the CPG consists of three pacema...

Effect of inhibitory spike-timing-dependent plasticity on fast sparsely synchronized rhythms in a small-world neuronal network.

Neural networks : the official journal of the International Neural Network Society
We consider the Watts-Strogatz small-world network (SWN) consisting of inhibitory fast spiking Izhikevich interneurons. This inhibitory neuronal population has adaptive dynamic synaptic strengths governed by the inhibitory spike-timing-dependent plas...

Mechanism-Based and Input-Output Modeling of the Key Neuronal Connections and Signal Transformations in the CA3-CA1 Regions of the Hippocampus.

Neural computation
This letter examines the results of input-output (nonparametric) modeling based on the analysis of data generated by a mechanism-based (parametric) model of CA3-CA1 neuronal connections in the hippocampus. The motivation is to obtain biological insig...

Stimulus-induced transitions between spike-wave discharges and spindles with the modulation of thalamic reticular nucleus.

Journal of computational neuroscience
It is believed that thalamic reticular nucleus (TRN) controls spindles and spike-wave discharges (SWD) in seizure or sleeping processes. The dynamical mechanisms of spatiotemporal evolutions between these two types of activity, however, are not well ...

Synchrony measure for a neuron driven by excitatory and inhibitory inputs and its adaptation to experimentally-recorded data.

Bio Systems
The aim of the current work is twofold: firstly to adapt an existing method measuring the input synchrony of a neuron driven only by excitatory inputs in such a way so as to account for inhibitory inputs as well and secondly to further appropriately ...

Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.

Scientific reports
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...

Tonic regulation of stationary asynchronous firing of a neural network.

Journal of computational neuroscience
The impact of tonic conductance upon population activity was investigated. An extra tonic transmembrane current through GABA-activated extrasynaptic GABA -receptors was found to control stationary asynchronous firing both quantitatively and qualitat...

Persistent irregular activity is a result of rebound and coincident detection mechanisms: A computational study.

Neural networks : the official journal of the International Neural Network Society
Persistent irregular activity is defined as elevated irregular neural discharges in the brain in such a way that while the average network activity displays high frequency oscillations, the participating neurons display irregular and low frequency os...

Neuronify: An Educational Simulator for Neural Circuits.

eNeuro
Educational software (apps) can improve science education by providing an interactive way of learning about complicated topics that are hard to explain with text and static illustrations. However, few educational apps are available for simulation of ...

Stability and instability of a neuron network with excitatory and inhibitory small-world connections.

Neural networks : the official journal of the International Neural Network Society
This study considers a delayed neural network with excitatory and inhibitory shortcuts. The global stability of the trivial equilibrium is investigated based on Lyapunov's direct method and the delay-dependent criteria are obtained. It is shown that ...