BACKGROUND: The BraTS Generalizability Across Tumors (BraTS-GoAT) initiative addresses the critical need for robust and generalizable models in brain tumor segmentation. Despite advancements in automated segmentation techniques, the variability in tu...
BACKGROUND: Early and timely detection of pulmonary nodules and initiation treatment can substantially improve the survival rate of lung carcinoma. However, current detection methods based on convolutional neural networks (CNNs) cannot easily detect ...
Antimicrobial peptides (AMPs) are promising candidates to combat multidrug-resistant pathogens. However, the high cost of extensive wet-lab screening has made AI methods for identifying and designing AMPs increasingly important, with machine learning...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
The interactions between long noncoding RNA (lncRNA) and protein play crucial roles in various biological processes. Computational methods are essential for predicting lncRNA-protein interactions and deciphering their mechanisms. In this chapter, we ...
Zhonghua wai ke za zhi [Chinese journal of surgery]
Jan 1, 2025
Robotic joint surgery (RJS) has demonstrated high precision and reproducibility in total hip and knee arthroplasty,the integration of artificial intelligence(AI) has further enhanced the intelligence level of key processes,including surgical planning...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2025
Alzheimer's disease (AD) is a neurocognitive disorder that deteriorates memory and impairs cognitive functions. Mild Cognitive Impairment (MCI) is generally considered as an intermediate phase between normal cognitive aging and more severe conditions...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2025
Precision medicine significantly enhances patients prognosis, offering personalized treatments. Particularly for metastatic cancer, incorporating primary tumor location into the diagnostic process greatly improves survival rates. However, traditional...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2025
Genetic perturbation of T cell receptor (TCR) T cells is a promising method to unlock better TCR T cell performance to create more powerful cancer immunotherapies, but understanding the changes to T cell behavior induced by genetic perturbations rema...
BACKGROUND: Osteoporosis (OP) is one of the most common diseases in the elderly population. It is mostly treated with medication, but drug research and development have the disadvantage of taking a long time and having a high cost.
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