AIMC Topic: Neurons
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Visualizing nuclear pore complex plasticity with pan-expansion microscopy.
The Journal of cell biology
Jun 12, 2025
The exploration of cell-type and environmentally responsive nuclear pore complex (NPC) plasticity requires new, accessible tools. Using pan-expansion microscopy (pan-ExM), NPCs were identified by machine learning-facilitated segmentation. They exhibi...
A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the ventral nerve cord.
eLife
Jun 10, 2025
Understanding developmental changes in neuronal lineages is crucial to elucidate how they assemble into functional neural networks. Studies investigating nervous system development in model systems have only focused on select regions of the CNS due t...
Spatial reasoning via recurrent neural dynamics in mouse retrosplenial cortex.
Nature neuroscience
Jun 6, 2025
From visual perception to language, sensory stimuli change their meaning depending on previous experience. Recurrent neural dynamics can interpret stimuli based on externally cued context, but it is unknown whether they can compute and employ interna...
Decreased spinal inhibition leads to undiversified locomotor patterns.
Biological cybernetics
Jun 4, 2025
During walking and running, animals display rich and coordinated motor patterns that are generated and controlled within the central nervous system. Previous computational and experimental results suggest that the balance between excitation and inhib...
Memristive neuromorphic interfaces: integrating sensory modalities with artificial neural networks.
Materials horizons
Jun 3, 2025
The advent of the Internet of Things (IoT) has led to exponential growth in data generated from sensors, requiring efficient methods to process complex and unstructured external information. Unlike conventional von Neumann sensory systems with separa...
Concept transfer of synaptic diversity from biological to artificial neural networks.
Nature communications
Jun 2, 2025
Recent developments in artificial neural networks have drawn inspiration from biological neural networks, leveraging the concept of the artificial neuron to model the learning abilities of biological nerve cells. However, while neuroscience has provi...
Hybrid neural networks in the mushroom body drive olfactory preference in .
Science advances
May 30, 2025
In , olfactory encoding in the mushroom body (MB) involves thousands of Kenyon cells (KCs) processing inputs from hundreds of projection neurons (PNs). Recent data challenge the notion of random PN-to-KC connectivity, revealing preferential connectio...
The Role of Hydrogen Sulfide in the Localization and Structural-Functional Organization of p53 Following Traumatic Brain Injury: Development of a YOLO Model for Detection and Quantification of Apoptotic Nuclei.
International journal of molecular sciences
May 24, 2025
Traumatic brain injury (TBI) triggers a cascade of molecular and cellular disturbances, including apoptosis, inflammation, and destabilization of neuronal connections. The transcription factor p53 plays a pivotal role in regulating cell fate followin...
Neuron-astrocyte associative memory.
Proceedings of the National Academy of Sciences of the United States of America
May 23, 2025
Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might collectivel...
Automated inference of disease mechanisms in patient-hiPSC-derived neuronal networks.
Communications biology
May 20, 2025
Human induced pluripotent stem cells (hiPSCs)-derived neuronal networks on multi-electrode arrays (MEAs) are a powerful tool for studying neurological disorders. The electric activity patterns of these networks differ between healthy and patient-deri...
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