AIMC Topic: Osteoarthritis
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Ensemble approach for predicting the diagnosis of osteoarthritis using physical activity factors.
Journal of evaluation in clinical practice
Oct 23, 2024
BACKGROUND: Osteoarthritis (OA) is a common degenerative disease of the joints. Risk factors for OA include non-modifiable factors such as age and sex, as well as modifiable factors like physical activity.
Machine learning algorithm-based biomarker exploration and validation of mitochondria-related diagnostic genes in osteoarthritis.
PeerJ
Sep 10, 2024
The role of mitochondria in the pathogenesis of osteoarthritis (OA) is significant. In this study, we aimed to identify diagnostic signature genes associated with OA from a set of mitochondria-related genes (MRGs). First, the gene expression profiles...
Evaluating and Enhancing Large Language Models' Performance in Domain-Specific Medicine: Development and Usability Study With DocOA.
Journal of medical Internet research
Jul 22, 2024
BACKGROUND: The efficacy of large language models (LLMs) in domain-specific medicine, particularly for managing complex diseases such as osteoarthritis (OA), remains largely unexplored.
Deep learning classification performance for diagnosing condylar osteoarthritis in patients with dentofacial deformities using panoramic temporomandibular joint projection images.
Oral radiology
Jul 11, 2024
OBJECTIVE: The present study aimed to assess the consistencies and performances of deep learning (DL) models in the diagnosis of condylar osteoarthritis (OA) among patients with dentofacial deformities using panoramic temporomandibular joint (TMJ) pr...
Classification of osteoarthritic and healthy cartilage using deep learning with Raman spectra.
Scientific reports
Jul 10, 2024
Raman spectroscopy is a rapid method for analysing the molecular composition of biological material. However, noise contamination in the spectral data necessitates careful pre-processing prior to analysis. Here we propose an end-to-end Convolutional ...
Characterizing mitochondrial features in osteoarthritis through integrative multi-omics and machine learning analysis.
Frontiers in immunology
Jul 4, 2024
PURPOSE: Osteoarthritis (OA) stands as the most prevalent joint disorder. Mitochondrial dysfunction has been linked to the pathogenesis of OA. The main goal of this study is to uncover the pivotal role of mitochondria in the mechanisms driving OA dev...
Identifying factors associated with locomotive syndrome using machine learning methods: The third survey of the research on osteoarthritis/osteoporosis against disability study.
Geriatrics & gerontology international
Jun 29, 2024
AIM: To identify factors associated with locomotive syndrome (LS) using medical questionnaire data and machine learning.
Automatic quantification of scapular and glenoid morphology from CT scans using deep learning.
European journal of radiology
Jun 25, 2024
OBJECTIVES: To develop and validate an open-source deep learning model for automatically quantifying scapular and glenoid morphology using CT images of normal subjects and patients with glenohumeral osteoarthritis.
Exploring liquid-liquid phase separation-related diagnostic biomarkers in osteoarthritis based on machine learning algorithms and experiment.
Immunobiology
Jun 9, 2024
BACKGROUND: Osteoarthritis (OA) is a prevalent joint disorder characterized by cartilage degeneration and joint inflammation. Liquid-liquid phase separation (LLPS), a biophysical process involved in cellular organization, has recently gained attentio...
Identification of ion channel-related genes as diagnostic markers and potential therapeutic targets for osteoarthritis through bioinformatics and machine learning-based approaches.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Jun 3, 2024
BACKGROUND: Osteoarthritis (OA) is a debilitating joint disorder characterized by the progressive degeneration of articular cartilage. Although the role of ion channels in OA pathogenesis is increasingly recognized, diagnostic markers and targeted th...
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