AIMC Topic: Parkinson Disease

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Machine learning for early detection and severity classification in people with Parkinson's disease.

Scientific reports
Early detection of Parkinson's disease (PD) and accurate assessment of disease progression are critical for optimizing treatment and rehabilitation. However, there is no consensus on how to effectively detect early-stage PD and classify motor symptom...

Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes.

PloS one
OBJECTIVES: Parkinson's disease (PD) is a complex neurodegenerative disease with unclear pathogenesis. Some recent studies have shown that there is a close relationship between PD and ferroptosis. We aimed to identify the ferroptosis-related genes (F...

A robust Parkinson's disease detection model based on time-varying synaptic efficacy function in spiking neural network.

BMC neurology
Parkinson's disease (PD) is a neurodegenerative disease affecting millions of people around the world. Conventional PD detection algorithms are generally based on first and second-generation artificial neural network (ANN) models which consume high e...

Computer model for gait assessments in Parkinson's patients using a fuzzy inference model and inertial sensors.

Artificial intelligence in medicine
Patients with Parkinson's disease (PD) in the moderate and severe stages can present several walk alterations. They can show slow movements and difficulty initiating, varying, or interrupting their gait; freezing; short steps; speed changes; shufflin...

Understanding Parkinson's: The microbiome and machine learning approach.

Maturitas
OBJECTIVE: Given that Parkinson's disease is a progressive disorder, with symptoms that worsen over time, our goal is to enhance the diagnosis of Parkinson's disease by utilizing machine learning techniques and microbiome analysis. The primary object...

Real-Time Freezing of Gait Prediction and Detection in Parkinson's Disease.

Sensors (Basel, Switzerland)
Freezing of gait (FOG) is a walking disturbance that can lead to postural instability, falling, and decreased mobility in people with Parkinson's disease. This research used machine learning to predict and detect FOG episodes from plantar-pressure da...

A pilot study for speech assessment to detect the severity of Parkinson's disease: An ensemble approach.

Computers in biology and medicine
BACKGROUND: Changes in voice are a symptom of Parkinson's disease and used to assess the progression of the condition. However, natural differences in the voices of people can make this challenging. Computerized binary speech classification can ident...

Machine Learning Recognizes Stages of Parkinson's Disease Using Magnetic Resonance Imaging.

Sensors (Basel, Switzerland)
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD) and Parkinson's disease (PD), are debilitating conditions that affect millions worldwide, and the number of cases is expected to rise significantly in the coming years. Because early ...

Machine Learning and Statistical Analyses of Sensor Data Reveal Variability Between Repeated Trials in Parkinson's Disease Mobility Assessments.

Sensors (Basel, Switzerland)
Mobility tasks like the Timed Up and Go test (TUG), cognitive TUG (cogTUG), and walking with turns provide insights into the impact of Parkinson's disease (PD) on motor control, balance, and cognitive function. We assess the test-retest reliability o...

Integrating bioinformatics and machine learning to uncover lncRNA LINC00269 as a key regulator in Parkinson's disease via pyroptosis pathways.

European journal of medical research
BACKGROUND: Pyroptosis, a specific type of programmed cell death, which has become a significant factor to Parkinson's disease (PD). Concurrently, long non-coding RNAs (lncRNAs) have garnered attention for their regulatory roles in neurodegenerative ...