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Positron-Emission Tomography

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An investigation of quantitative accuracy for deep learning based denoising in oncological PET.

Physics in medicine and biology
Reducing radiation dose is important for PET imaging. However, reducing injection doses causes increased image noise and low signal-to-noise ratio (SNR), subsequently affecting diagnostic and quantitative accuracies. Deep learning methods have shown ...

mDixon-Based Synthetic CT Generation for PET Attenuation Correction on Abdomen and Pelvis Jointly Using Transfer Fuzzy Clustering and Active Learning-Based Classification.

IEEE transactions on medical imaging
We propose a new method for generating synthetic CT images from modified Dixon (mDixon) MR data. The synthetic CT is used for attenuation correction (AC) when reconstructing PET data on abdomen and pelvis. While MR does not intrinsically contain any ...

Prediction of Chemotherapy Response of Osteosarcoma Using Baseline F-FDG Textural Features Machine Learning Approaches with PCA.

Contrast media & molecular imaging
PURPOSE: Patients with high-grade osteosarcoma undergo several chemotherapy cycles before surgical intervention. Response to chemotherapy, however, is affected by intratumor heterogeneity. In this study, we assessed the ability of a machine learning ...

Use of a Tracer-Specific Deep Artificial Neural Net to Denoise Dynamic PET Images.

IEEE transactions on medical imaging
Application of kinetic modeling (KM) on a voxel level in dynamic PET images frequently suffers from high levels of noise, drastically reducing the precision of parametric image analysis. In this paper, we investigate the use of machine learning and a...

Using an artificial neural network for fast mapping of the oxygen extraction fraction with combined QSM and quantitative BOLD.

Magnetic resonance in medicine
PURPOSE: To apply an artificial neural network (ANN) for fast and robust quantification of the oxygen extraction fraction (OEF) from a combined QSM and quantitative BOLD analysis of gradient echo data and to compare the ANN to a traditional quasi-New...

Novel adversarial semantic structure deep learning for MRI-guided attenuation correction in brain PET/MRI.

European journal of nuclear medicine and molecular imaging
OBJECTIVE: Quantitative PET/MR imaging is challenged by the accuracy of synthetic CT (sCT) generation from MR images. Deep learning-based algorithms have recently gained momentum for a number of medical image analysis applications. In this work, a no...

F-FDG-PET-based radiomics features to distinguish primary central nervous system lymphoma from glioblastoma.

NeuroImage. Clinical
The differential diagnosis of primary central nervous system lymphoma from glioblastoma multiforme (GBM) is essential due to the difference in treatment strategies. This study retrospectively reviewed 77 patients (24 with lymphoma and 53 with GBM) to...

Imaging Quality Control in the Era of Artificial Intelligence.

Journal of the American College of Radiology : JACR
The advent of artificial intelligence (AI) promises to have a transformational impact on quality in medicine, including in radiology. However, experience has shown that quality tools alone are often not sufficient to bring about consistent excellent ...

Deep-learning-based imaging-classification identified cingulate island sign in dementia with Lewy bodies.

Scientific reports
The differentiation of dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) using brain perfusion single photon emission tomography is important but is challenging because these conditions exhibit typical features. The cingulate island sign ...

Ultra-low-dose PET reconstruction using generative adversarial network with feature matching and task-specific perceptual loss.

Medical physics
PURPOSE: Our goal was to use a generative adversarial network (GAN) with feature matching and task-specific perceptual loss to synthesize standard-dose amyloid Positron emission tomography (PET) images of high quality and including accurate pathologi...