AIMC Topic: Prenatal Diagnosis

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Identification of suspicious invasive placentation based on clinical MRI data using textural features and automated machine learning.

European radiology Aug 23, 2019
OBJECTIVE: The aim of this study was to investigate whether intraplacental texture features from routine placental MRI can objectively and accurately predict invasive placentation.
Humans Machine Learning Algorithms Retrospective Studies Magnetic Resonance Imaging Placenta Placentation Prenatal Diagnosis Placenta Previa Pregnancy Female Young Adult Adult
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Automatic brain tissue segmentation in fetal MRI using convolutional neural networks.

Magnetic resonance imaging Jun 7, 2019
MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes. Manual segment...
Prenatal Diagnosis Magnetic Resonance Imaging Image Interpretation, Computer-Assisted Artifacts Brain Diseases Brain Pregnancy Female Humans Neural Networks, Computer
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Machine learning analysis of MRI-derived texture features to predict placenta accreta spectrum in patients with placenta previa.

Magnetic resonance imaging May 15, 2019
PURPOSE: To evaluate whether a machine learning (ML) analysis employing MRI-derived texture analysis (TA) features could be useful in assessing the presence of placenta accreta spectrum (PAS) in patients with placenta previa (PP). The hypothesis is t...
Humans Machine Learning Algorithms Retrospective Studies Pregnancy Image Interpretation, Computer-Assisted Prenatal Diagnosis Placenta Accreta Placenta Previa Magnetic Resonance Imaging Female Predictive Value of Tests Reproducibility of Results Bayes Theorem Adult Placenta Sensitivity and Specificity
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Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination.

PloS one Dec 5, 2018
With the advance of next-generation sequencing (NGS) technologies, non-invasive prenatal testing (NIPT) has been developed and employed in fetal aneuploidy screening on 13-/18-/21-trisomies through detecting cell-free fetal DNA (cffDNA) in maternal b...
Female Young Adult Adult Diagnosis, Computer-Assisted Diagnosis, Differential Genetic Testing High-Throughput Nucleotide Sequencing Support Vector Machine Sequence Analysis, DNA Humans Machine Learning Retrospective Studies Pregnancy Trisomy 13 Syndrome Down Syndrome Trisomy 18 Syndrome False Negative Reactions False Positive Reactions Prenatal Diagnosis
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Evaluation of machine learning algorithms for improved risk assessment for Down's syndrome.

Computers in biology and medicine May 4, 2018
Prenatal screening generates a great amount of data that is used for predicting risk of various disorders. Prenatal risk assessment is based on multiple clinical variables and overall performance is defined by how well the risk algorithm is optimized...
Pregnancy Female Adult Risk Assessment ROC Curve Humans Neural Networks, Computer Machine Learning Algorithms Support Vector Machine Models, Statistical Down Syndrome Prenatal Diagnosis
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Two-stage approach for risk estimation of fetal trisomy 21 and other aneuploidies using computational intelligence systems.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology Mar 4, 2018
OBJECTIVE: To estimate the risk of fetal trisomy 21 (T21) and other chromosomal abnormalities (OCA) at 11-13 weeks' gestation using computational intelligence classification methods.
Humans Artificial Intelligence Pregnancy Female Pregnancy Trimester, First Down Syndrome Prenatal Diagnosis Sensitivity and Specificity Risk Assessment
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Application of Neural Networks for classification of Patau, Edwards, Down, Turner and Klinefelter Syndrome based on first trimester maternal serum screening data, ultrasonographic findings and patient demographics.

BMC medical genomics Feb 13, 2018
BACKGROUND: The usage of Artificial Neural Networks (ANNs) for genome-enabled classifications and establishing genome-phenotype correlations have been investigated more extensively over the past few years. The reason for this is that ANNs are good ap...
Trisomy 13 Syndrome Trisomy 18 Syndrome Klinefelter Syndrome Turner Syndrome Mothers Down Syndrome Demography Prenatal Diagnosis Female Young Adult Adult Male Ultrasonography Humans Computational Biology Neural Networks, Computer Pregnancy Trimester, First Pregnancy Middle Aged Adolescent
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Intelligent Noninvasive Diagnosis of Aneuploidy: Raw Values and Highly Imbalanced Dataset.

IEEE journal of biomedical and health informatics Dec 22, 2016
The objective of this paper is to introduce a noninvasive diagnosis procedure for aneuploidy and to minimize the social and financial cost of prenatal diagnosis tests that are performed for fetal aneuploidies in an early stage of pregnancy. We propos...
Models, Statistical Aneuploidy Down Syndrome Prenatal Diagnosis Biomarkers Humans Female Pregnancy Neural Networks, Computer Ultrasonography, Prenatal Machine Learning Computational Biology Databases, Factual
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Robust Wavelet Stabilized 'Footprints of Uncertainty' for Fuzzy System Classifiers to Automatically Detect Sharp Waves in the EEG after Hypoxia Ischemia.

International journal of neural systems Aug 18, 2016
Currently, there are no developed methods to detect sharp wave transients that exist in the latent phase after hypoxia-ischemia (HI) in the electroencephalogram (EEG) in order to determine if these micro-scale transients are potential biomarkers of H...
Sheep, Domestic Prenatal Diagnosis Uncertainty Fetal Hypoxia Disease Models, Animal Electroencephalography Machine Learning Brain Ischemia Pregnancy Wavelet Analysis Animals Cohort Studies Fuzzy Logic Female Sensitivity and Specificity
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Isolation and analysis of cell-free fetal DNA from maternal peripheral blood in Chinese women.

Genetics and molecular research : GMR Dec 22, 2015
Non-invasive prenatal diagnosis is used to detect the genetic material of the fetus by isolating the cell-free fetal DNA (cffDNA) from maternal peripheral blood. In order to establish an isolation method for cffDNA from maternal peripheral blood in C...
Chromosomes, Human, Y SOXB1 Transcription Factors DNA Humans Fetus Pregnancy Gestational Age Female Prenatal Diagnosis Adult
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