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Principal Component Analysis

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Exon level machine learning analyses elucidate novel candidate miRNA targets in an avian model of fetal alcohol spectrum disorder.

PLoS computational biology
Gestational alcohol exposure causes fetal alcohol spectrum disorder (FASD) and is a prominent cause of neurodevelopmental disability. Whole transcriptome sequencing (RNA-Seq) offer insights into mechanisms underlying FASD, but gene-level analysis pro...

Midterm Power Load Forecasting Model Based on Kernel Principal Component Analysis and Back Propagation Neural Network with Particle Swarm Optimization.

Big data
To improve the accuracy of midterm power load forecasting, a forecasting model is proposed by combing kernel principal component analysis (KPCA) with back propagation neural network. First, the dimension of the input space is reduced by KPCA, then in...

Development of a Strategy to Predict and Detect Falls Using Wearable Sensors.

Journal of medical systems
Falls are a prevalent problem in actual society. Some falls result in injuries and the cost associated with their treatment is high. This is a complex problem that requires several steps in order to be tackled. Firstly, it is crucial to develop strat...

Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression.

Medical & biological engineering & computing
In this study, an electrochemical impedance biosensor was developed as a simple and fast method for real-time monitoring of biofilm binding properties via continuous impedance spectroscopy. To prepare the sensing membrane, cells were immobilized onto...

Patient-Specific Seizure Detection Method using Hybrid Classifier with Optimized Electrodes.

Journal of medical systems
In this paper the EEG signal is analyzed by reconstructing the time series EEG signal in High dimensional Phase Space. The computational complexity in higher dimension is reduced by Principal Component Analysis for the High dimensional Phase Space ou...

Analysis of Machine Learning Algorithms for Diagnosis of Diffuse Lung Diseases.

Methods of information in medicine
UNLABELLED: Computational Intelligence Re-meets Medical Image Processing A Comparison of Some Nature-Inspired Optimization Metaheuristics Applied in Biomedical Image Registration BACKGROUND:  Diffuse lung diseases (DLDs) are a diverse group of pulmon...

Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome.

Journal of affective disorders
BACKGROUND: Both of the modern medicine and the traditional Chinese medicine classify depressive disorder (DD) and chronic fatigue syndrome (CFS) to one type of disease. Unveiling the association between depressive and the fatigue diseases provides a...

A combined drug discovery strategy based on machine learning and molecular docking.

Chemical biology & drug design
Data mining methods based on machine learning play an increasingly important role in drug design and discovery. In the current work, eight machine learning methods including decision trees, k-Nearest neighbor, support vector machines, random forests,...

Scaled Subprofile Modeling and Convolutional Neural Networks for the Identification of Parkinson's Disease in 3D Nuclear Imaging Data.

International journal of neural systems
Over the last years convolutional neural networks (CNNs) have shown remarkable results in different image classification tasks, including medical imaging. One area that has been less explored with CNNs is Positron Emission Tomography (PET). Fluorodeo...